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It is also used to prevent certain skin cancers squamous-cell carcinoma, and in the treatment of other cancers. The most common adverse effects are a transient worsening of acne lasting 1—4 months, dry lips cheilitis, dry and fragile skin, buy accutane cheap online an increased susceptibility to sunburn. Isotretinoin is known to cause birth defects due to in-utero exposure because of the molecule's close resemblance to retinoic acid, a natural vitamin A derivative which controls normal embryonic development. In the United States, a special procedure is required to obtain the pharmaceutical. In other countries, such as Israel, it is prescribed like any other medicine from a dermatologist after proper blood tests.

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