Besides involvement of skin, fibrosis also affects lung and heart. The investigators have conducted three clinical trials with PDE5 inhibitor Tadalafil in the refractory Raynaud's phenomenon RP in SSc over last 3 years and had found good response in RP, healing of digital ulcers, prevention of new digital ulcers and also observed improvement in skin tightening, endothelial dysfunction and improvement of quality of life. The investigators therefore hypothesize that tadalafil may have an efficacy in improving the ILD of SSc. The investigators therefore design this double-blind, randomized, placebo-controlled trial of oral Tadalafil 20 mg alternate day in patients with SSc having ILD. The primary objective of the study will be the change in FVC expressed as a percentage of the predicted value from baseline values at the end of 6-months of treatment.

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Your health, for today and for future. Tadalafil is a selective, reversible inhibitor of specific phosphodiesterase type 5 PDE5. Drug tadalafil tablets 1 mg an erection in the presence of sexual stimulation. Used in the management of erectile dysfunction. Tadalafil is effective only in the presence of adequate sexual stimulation. Usual dose: 10 mg at least 30 minutes before sexual intercourse.

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It is sometimes known by its generic name tadalafil, and sometimes known by its tadalafil tablet 1 mg name, Cialis. There are also other brands of this medicine available. Tadalafil works by helping to relax the blood vessels in the penis, allowing blood to flow more easily into the penis. If you have erectile dysfunction, this can make it easier to get an erection. If you have BPH, this can improve your urinary symptoms. If you plan to use tadalafil, you should take it 30 to 60 minutes before planned sexual activity.

In erectile dysfunction, it works by increasing blood flow to the penis by relaxing the muscles in penile blood vessels. In benign prostatic hyperplasia BPH, it helps relax the muscles in the prostate gland and the bladder to relieve urinary symptoms. Common side effects of Tadalafil Flushing sense of warmth in the face, ears, neck and trunk, Headache, Muscle pain, Nasal congestion stuffy nose, Back pain, Pain in extremities, Dyspepsia. Forzest Sun Pharmaceutical Industries Ltd. Modula Sun Pharmaceutical Industries Ltd.

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Yellow, capsule shaped, approximately Treatment should only be initiated and monitored by a physician experienced in the treatment of PAH. Adult men with erectile dysfunction: Dose adjustments are not required in patients with mild to moderate renal impairment. Pulmonary arterial hypertension: In patients with mild to moderate renal impairment a starting dose of 20 mg once per day is recommended. The dose may be increased to 40 mg once per day, based on individual efficacy and tolerability. In patients with severe renal impairment the use of tadalafil is not recommended.

Tadalafil is used to treat male sexual function problems impotence or erectile dysfunction -ED. In combination with sexual stimulation, tadalafil works by increasing blood flow to the penis to help a man get and keep an erection. Tadalafil is also used to treat the symptoms of an enlarged prostate benign prostatic hyperplasia - BPH. It helps to relieve symptoms of BPH such as difficulty in beginning the flow of urine, weak stream, and the need to urinate frequently or urgently including during the middle of the night. Tadalafil is thought to work by relaxing the smooth muscle in the prostate and bladder. This drug does not protect against sexually transmitted diseases such as HIV, hepatitis B, gonorrhea, syphilis.

Tadalafil Once Daily comes in two strengths — 2. Ordering Tadalafil Daily online through The Independent Pharmacy is easy — simply complete a quick consultation with one of our healthcare professionals. The decision to supply the specific treatment and quantity requested will be based on whether our medical team are satisfied that it will be safe, appropriate, and effective. To clarify, Tadalafil is just the generic equivalent to Cialis, a branded drug used to treat erectile dysfunction and benign prostatic hyperplasia BPH, an enlargement of the prostate. Tadalafil is just as effective as Cialis, and is on sale in the UK thanks to the recent patent expiration on the Cialis brand name.

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