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Co-administration of simvastatin with amlodipine increases the systemic exposure of simvastatin. Worsening angina and acute myocardial infarction can develop after starting or increasing the dose of amlodipine, particularly in patients with severe obstructive coronary artery disease. Gastrointestinal Disorders: Diarrhea, nausea, constipation, dyspepsia, abdominal pain, abdominal pain upper, gastritis, vomiting, abdominal discomfort, abdominal distention, dry mouth, colitis.
For convenience, patients receiving amlodipine and valsartan from separate tablets may instead wish to receive tablets of Exforge containing the same component doses. Respiratory, Thoracic and Mediastinal Disorders: Cough, pharyngolaryngeal pain, sinus congestion, dyspnea, epistaxis, productive cough, dysphonia, nasal congestion.
In trials in which valsartan was compared to an ACE inhibitor with or without placebo, the incidence of dry cough was significantly greater in the ACE inhibitor group 7. Exforge amlodipine and valsartan is indicated for the treatment of hypertension, to lower blood pressure. Exforge may be used in patients whose blood pressure is not adequately controlled on either monotherapy. The majority of the antihypertensive effect is attained within 2 weeks after initiation of therapy or a change in dose.
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. Some patients with heart failure have developed increases in potassium with valsartan therapy. Blood pressure should be closely monitored when amlodipine is co-administered with CYP3A inducers. Special Senses: abnormal vision, conjunctivitis, diplopia, eye pain, tinnitus.
Exforge may be used alone or buy cialis cvs other medications. These are not all the possible side effects of Exforge. Exforge contains the besylate salt of amlodipine, a dihydropyridine calcium-channel blocker CCB.
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