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This article reflects the scientific opinion of the authors and not the policies of regulating agencies and the International Pharmaceutical Federation FIP. The purpose and scope of this series of monographs have been previously discussed. A search in the PubMed Central and Scirus was conducted using the keywords ciprofloxacin and ciprofloxacin hydrochloride combined with: absorption, absolute bioavailability BA, bioequivalence BE, dissolution, excipients, partition coefficient, permeability, pharmacokinetics, polymorphism, oral, and solubility. Whenever possible, original literature was consulted and data from secondary sources were included for completeness or when original literature could not be located. Ciprofloxacin is a broad-spectrum bactericidal antiinfective agent of the fluoroquinolone class.

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