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They can be administered by qualified, registered and trained radiographers under patient group directions. Analgesia may be necessary for the after-effects of venepuncture or following therapeutic radiographic procedures. Peripherally acting analgesics, for example paracetamol, aspirin or ibuprofen should be sufficient.

Dithranol can cause inflammation, so initially concentrations no greater than should be applied for off. If this is tolerated, higher concentrations can be used to provide optimum response. Since dithranol irritates normal skin, it should not be used in flexures, on the face or in skin folds.

Chloroquine and hydroxychloroquine are normally used to treat malaria. In inflammatory disease their exact mode of action is unknown but they inhibit the migration of leukocytes and proliferation of lymphocytes in rheumatoid arthritis. They also reduce release of enzymes in phagocytic cells and inhibit phospholipase A prostaglandin and leukotriene synthesis. Chloroquine and hydroxychloroquine are sometimes used to treat systemic and discoid lupus erythematosus, but should not be used for psoriatic arthritis. Because of the risk of retinopathy, long-term therapy should be reserved for cases in which all other DMARDs have failed.

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Factors affecting compliance in older people are many and include the complexity of multiple therapy, possible difficulty in understanding instructions, ambiguous or unclear patient information or labelling, preconceived ideas about medicines and their benefits, previous bad experience, difficult dosing regimes, unpalatable formulations and real or imagined side effects. As we get older, there are physiological changes that can alter the effect a drug has on the body. This is difficult to prove as it involves the increase in the sensitivity of drug receptors with age. It seems to be of importance with drugs such as the benzodiazepines and warfarin. In addition existing organ pathology such as renal or hepatic disease can affect drug response.

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The persons most likely to be best informed of these changes are pharmacy staff. Controlled drugs are further classified according to the degree of danger that misuse of them presents and for determining penalties for offences under the Act. Non-medical prescribing is the term applied to prescribing by members of the health care professions who are not medically qualified.

The granulomas contain bacteria lying dormant but capable of becoming reactivated later in the patients life if they become ill from some other cause or become immunosuppressed. Treatment for tuberculosis is lengthy taking up to two years and requiring combinations of at least three different antibiotics. First line drugs used to treat tuberculosis include isoniazid, rifampicin and pyrazinamide with streptomycin and ethambutol as secondary drugs. Antibiotics for tuberculosis are discussed in Chapter Common respiratory disorders are asthma and chronic bronchitis. Asthma is often, but not always, caused by an allergic response and bronchitis is caused by chronic irritation cytotec 50cpr 200mcg online the lungs.

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