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Dapagliflozin, a selective sodium-glucose cotransporter 2 SGLT2 inhibitor, reduces hyperglycemia in patients with type 2 diabetes mellitus T2DM by increasing urinary glucose excretion, and weight loss is a consistent associated finding. Included were patients with T2DM mean values: women

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Diabetes Mellitus DM is a heterogeneous group of metabolic disorders characterized by hyperglycemia, the presence of insulin resistance, and inadequate compensatory insulin secretion. Risk factors include family history, obesity, and a hemoglobin A1C 5. In, 26 million Americans 20 and older had DM, and it contributes to 65, lower-extremity amputations annually. The limitations of use are that it is not indicated for type 1 DM or diabetic ketoacidosis and should only be used in patients who tolerate 10 mg dapagliflozin. Dapagliflozin is a sodium glucose co-transporter 2 inhibitor. Buy metformin er reduces reabsorption of filtered glucose and lowers the renal threshold for glucose, resulting in increased urinary glucose excretion.

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