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Duloxetine, sold under the brand name Cymbalta among others, 1 is a medication used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Duloxetine is a serotonin—norepinephrine reuptake inhibitor SNRI. Common side effects include dry mouth, nausea, feeling tired, dizziness, agitation, sexual problems, and increased sweating. Duloxetine was approved for medical use in the United States and in the European Union in The main uses of duloxetine are in major depressive disorder, generalized anxiety disorder, neuropathic pain, chronic musculoskeletal pain, and fibromyalgia. Duloxetine is recommended as a first-line agent for the treatment of chemotherapy-induced neuropathy by the American Society of Clinical Oncology, 13 as a first-line therapy for fibromyalgia in the presence of mood disorders by the German Interdisciplinary Association for Pain Therapy, 14 as a Grade B recommendation for the treatment of diabetic neuropathy by the American Association for Neurology 15 and as a level A recommendation in certain neuropathic states by the European Federation of Neurological Societies. Duloxetine was approved for the treatment of major depression in

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I was in an accident 3 months ago. I had extreme pain and finally I found a doctor who listened to me. After my accident and my lower buttocks legs and heels I could hardly move not including all the neck problems I had the first wee. I first had my body a little flu like feeling, in my mind a little foggy, however if you're really taking this for nerve pain I would suggest this to anyone it has helped me more than anything. Those that I'm aware I've encountered that are attributable to this drug, order of impairment include: insomnia, excessive sweating, picking, constipation, dry mouth. In the time I've been on cymbalta for peripheral nerve pain, I have worked hard at improving my health overall some metrics include having lost 80lbs, reduced a1c from 6.

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