Statins competitively inhibit 3-hydroxymethylglutaryl coenzyme A HMG CoA reductase, an enzyme involved in cholesterol synthesis, especially in the liver. Initially 5 mg daily with concurrent use of bezafibrate, ciprofibrate, and fenofibrate—40 mg dose is contraindicated. Initially 5 mg daily with concurrent use of clopidogrel—max. Initially 5 mg daily with concurrent use of elbasvir with grazoprevir—max. Reduce dose by half with concurrent use of teriflunomide. Initially 5 mg daily with concurrent use of atazanavir boosted with ritonavir—max. Initially 5 mg daily with concurrent use of lopinavir boosted with ritonavir—max.

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Your doctor may also prescribe rosuvastatin if you have diabetes, kidney disease, or a family history of rheumatoid arthritis or heart disease. Rosuvastatin also comes as a higher 40mg dose for adults. It's not suitable for some people. Tell your doctor if you also It's usual to take rosuvastatin once a day. You can take it at any time as long as you stick to the same time every day. Sometimes a lower dose may be prescribed. If needed, your doctor may increase your dose every 4 weeks up to 20mg a day. If you have very high cholesterol, you may be prescribed a higher dose of 40mg a day by a specialist.

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It is used, along with a healthy diet and exercise program, to improve cholesterol levels by lowering bad cholesterol and raising erythromycin estolate 250 mg cholesterol. It is also used to treat people who have certain inherited cholesterol disorders. Rosuvastatin works by blocking the enzyme that helps make cholesterol in the body. People with high blood cholesterol levels have a higher risk of heart diseases such as heart attacks. When cholesterol levels are lowered with a combination of medication, diet, and exercise, the risk of heart disease is lowered. It takes 2 to 4 weeks to see the maximum effect of this medication on cholesterol levels in blood tests.

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Nirmatrelvir must be co-administered with ritonavir. Failure to correctly co-administer nirmatrelvir with ritonavir may result in plasma levels of nirmatrelvir that are insufficient to achieve the desired therapeutic effect. Completion of the full 5-day treatment course and continued isolation in accordance with public health recommendations are important to maximize viral clearance and minimize transmission of SARS-CoV If the patient misses a dose of PAXLOVID within 8 hours of the time it is usually taken, the patient should take it as soon as possible and resume the normal dosing schedule. If the patient misses a dose by more than 8 hours, the patient should not take the missed dose and instead take the next dose at the regularly scheduled time.

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The application sought a restricted benefit listing of rosuvastatin for the treatment of hypercholesterolaemia. Prior to initiating therapy with Crestor, secondary causes of hypercholesterolaemia e. It provides an alternative treatment option to other members of this class for the lowering of lipid levels. The submission nominated atorvastatin and simvastatin as the comparators. The PBAC considered atorvastatin was the most appropriate, as this is the drug that will principally be replaced in practice.

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It also lowers the rosuvastatin calcium 5 mg of heart attacks and strokes. Do not use Crestor if you are pregnant or intend to become pregnant. Ask your doctor about effective methods of contraception. If you become pregnant, stop taking Crestor as soon as you find out and see your doctor immediately. Do not use Crestor if you are breastfeeding. It is not known if your baby can take in Crestor from breast milk if you are breast feeding.

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