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Streptokinase is antigenic and may provoke an allergic reaction, so it should not be used too often. Adverse reactions are nausea and vomiting and bleeding. Anaemia results when, for whatever reason, there is not enough haemoglobin in the blood to carry sufficient oxygen around to the tissues. Typical symptoms of anaemia are fatigue due to anoxia and intolerance to cold and paleness due to low levels of haemoglobin.

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This is a rapid event, occurring in milliseconds, which indicates that the receptor is directly connected to the channel. These are receptors for many hormones and neurotransmitters and are coupled to effector systems by a G-protein. The β-adrenoreceptor was the first of this type to be characterized and others seem to be similar. The structure is a single polypeptide chain spanning the membrane, folded into seven transmembrane domains and coupled to a G-protein. G-proteins are found on the inside of the membrane and act as transducers between receptors and cellular effectors.

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