Medroxyprogesterone contraceptive injections and oral tablets are contraindicated in patients with pre-existing breast cancer. Medroxyprogesterone depot injection suspension for the treatment of endometrial or renal cancer should generally not be used in women with a history of breast cancer, as breast cancer may be hormonally sensitive. Women with a strong family history of breast cancer should be monitored with particular care. Do not use medroxyprogesterone products in patients with undiagnosed abnormal genital or vaginal bleeding. In the same WHI substudy, invasive breast cancers were larger, were more likely to be node positive, and were diagnosed at a more advanced stage in the combined HRT group compared with the placebo group. Metastatic disease was rare, with no apparent difference between the 2 groups.

Dysfunctional anovulatory uterine bleeding: 2. Treatment should be given for two consecutive cycles. When bleeding occurs from a poorly developed proliferative endometrium, conventional oestrogen therapy may be employed in conjunction with medroxyprogesterone acetate in doses of 5 - 10 mg for 10 days. Repeat the treatment for three consecutive cycles. In amenorrhoea associated with a poorly developed proliferative endometrium, conventional oestrogen therapy may be employed in conjunction with medroxyprogesterone acetate in doses of 5 - 10 mg for 10 days. Breakthrough bleeding, which is self-limiting, may occur.

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Medroxyprogesterone acetate is a type of hormonal therapy drug to treat womb, kidney, and breast cancer. It is also known as Provera. Medroxyprogesterone is also occasionally used as a treatment for poor appetite. Your doctor may suggest that you take it if you are losing weight because it can help to boost your appetite. Progestogens act like progesterone, which is a sex hormone. Hormones are natural substances made by glands in our bodies. They are carried around our body in our bloodstream and act as messengers between one part of our body and another. Hormones are responsible for many functions in our body, including the growth and activity of certain cells and organs. Some cancers use hormones to grow or develop. This means the cancer is hormone sensitive or hormone dependent.

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It is used to treat various disorders of the menstrual cycle for example Like all medicines Provera can cause side effects, although not everyone gets them. Reasons for stopping Provera treatment immediately: Rarely, Provera may cause a severe allergic reaction which can be life-threatening in some cases. If you think you re reacting badly to the medicine get emergency medical help immediately. These could all be warning signs of thrombosis a blood clot which will need urgent treatment.

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Start at the lowest dose and talk to your healthcare provider about how well that dose is working for you. You and your healthcare provider should talk regularly every 3 to 6 months about the dose you are taking and whether you still need treatment with PROVERA. Side effects are grouped by how serious they are and how often they happen when you are treated. Tell your healthcare provider if you have side effect that bothers you or does not go away. Do not use estrogens with progestins to prevent heart disease, heart attacks, strokes, or dementia decline in brain function.

However, your pharmacist may have suggested a different schedule that is more appropriate for you. Do not use more of this product, cheap sinequan more often, than prescribed. Each person may react differently to a treatment. If you think this medication may be causing side effects including those described here, or others, talk to your health care professional. He or she can help you to determine whether or not the medication is the source of the problem. Make sure that any leftover portion is disposed of safely.

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Active thrombophlebitis, or current or past history of thromboembolic disorders, or cerebral vascular disease. Use caution in patients with asthma, diabetes mellitus, history of depression, epilepsy, migraine, porphyria, systemic lupus erythematosus, and hepatic hemangiomas. If used with conjugated decadron 6 mg iv, may increase risk of MI, stroke, pulmonary emboli, DVT, breast cancer; discontinue therapy in patients who develop thrombosis. Most women using depo-subQ medroxyprogesterone experienced changes in menstrual bleeding patterns, such as amenorrhea, irregular unpredictable spotting or bleeding, prolonged spotting or bleeding, or heavy bleeding; in cases of unexpected abnormal vaginal bleeding, adequate diagnostic measures are indicated. In women with preexisting hypertriglyceridemia, estrogen therapy may be associated with elevations of plasma triglycerides leading to pancreatitis; consider discontinuation of treatment if pancreatitis occurs. Progestins may cause some degree of fluid retention; women with condition influenced by fluid retention including epilepsy, migraine, asthma, cardiac or renal dysfunction, require careful observation.

Estrogen plus progestin therapy should not be used for the prevention of cardiovascular disease or dementia. The WHI estrogen plus progestin substudy demonstrated an increased risk of invasive breast cancer. Progestins with estrogens should be prescribed at the lowest effective doses and for the shortest duration consistent with treatment goals and risks for the individual woman. They are also indicated for use in the prevention of endometrial hyperplasia in nonhysterectomized postmenopausal women who are receiving daily oral conjugated estrogens 0. In cases of secondary amenorrhea, therapy may be started at any time. Patients with a past history of recurrent episodes of abnormal uterine bleeding may benefit from planned menstrual cycling with PROVERA.

Your dose of medroxyprogesterone will depend on what you are being treated for. Your doctor or pharmacist will tell you how many tablets to take and how often to take them. The cells in this tissue need oestrogen another female sex hormone to grow and survive. Medroxyprogesterone reduces the effect of oestrogen on these cells which causes them to 'shrink'. Medroxyprogesterone is also prescribed although at higher doses than in the conditions mentioned above to help treat some cancers, particularly endometrial cancer. Medroxyprogesterone is also available as an injection to prevent pregnancy, and as tablets in combination with an oestrogen for hormone replacement therapy HRT during the menopause.

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