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Medrol Tablet contains methylprednisolone which is a glucocorticoid. Endocrine Disorders: Primary or secondary adrenocortical insufficiency hydrocortisone or cortisone is the first choice; synthetic analogs may be used in conjunction with mineralocorticoids, where applicable, in infancy, mineralocorticoid supplementation is of particular importance ; congenital adrenal hyperplasia; non-suppurative thyroiditis; hypercalcemia associated with cancer. Non-Endocrine Disorders: Rheumatic Disorders: As adjunctive therapy for short-term administration to tide the patient over an acute episode or exacerbation in: Rheumatoid arthritis, including juvenile rheumatoid arthritis selected cases may require low dose maintenance therapy ; ankylosing spondylitis; synovitis of osteoarthritis; acute non-specific tenosynovitis; post-traumatic osteoarthritis; psoriatic arthritis; epicondylitis; acute gouty arthritis; acute and subacute bursitis. Collagen Diseases: During an exacerbation or as maintenance therapy in selected cases of: Systemic lupus erythematosus; polymyalgia rheumatica; giant cell arteritis; systemic dermatomyositis polymyositis ; acute rheumatic carditis. Ophthalmic Diseases: Severe acute and chronic allergic and inflammatory processes involving the eye and its adnexa, such as: Allergic corneal marginal ulcers; herpes zoster ophthalmicus; anterior segment inflammation; diffuse posterior uveitis and choroiditis; sympathetic ophthalmia; keratitis; optic neuritis; allergic conjunctivitis; chorioretinitis; iritis and iridocyclitis.

Rheumatic Disorders: Rheumatoid Arthritis. Juvenile Rheumatoid Arthritis, Ankylosing. Neoplastic Diseases: For palliative management of Leukemias and Lymphomas in adults, Acute leukemia of childhood. Edematous States: To induce a diuresis or remission of Proteinuria in the Nephrotic Syndrome, without Uremia, of the idiopathic type or that due to Lupus Erythematosus. Medrol is a potent anti-inflammatory steroid. It has greater anti-inflammatory potency than Prednisolone, even less tendency than prednisolone to induce sodium and water retention.

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Methylprednisolone acetate: Usual dosing range, mg IM every weeks; as temporary substitute for PO, given in daily IM dose equal to daily PO dose; for prolonged effect, given in weekly IM dose equal to 7 times daily PO dose; unlike methylprednisolone sodium succinate, may not be given IV. Methylprednisolone: Usual medrol tablet price range, 0. Use with caution in cirrhosis, ocular herpes simplex, hypertension, diverticulitis, hypothyroidism, myasthenia gravis, peptic ulcer disease, osteoporosis, ulcerative colitis, psychotic tendencies, renal insufficiency, pregnancy, diabetes mellitus, history of seizure disorders, multiple sclerosis, thromboembolic disorders, myocardial infarction. Use in septic shock or sepsis syndrome not proven effective and may increase mortality in some patients including patients with elevated serum creatinine and patients who develop secondary infections. Clearance of corticosteroids may increase in hyperthyroid patients and decrease in hypothyroid ones; dose adjustments may be necessary.

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