Common side effects include dry mouth, nausea, feeling tired, dizziness, agitation, sexual problems, and increased sweating. Duloxetine was approved for medical use in the United States in Duloxetine is recommended as a first-line agent for the treatment of chemotherapy-induced neuropathy by the American Society of Clinical Oncology, as a first-line therapy for fibromyalgia in the presence of mood disorders by the German Interdisciplinary Association for Pain Therapy, as a Grade B recommendation for the treatment of diabetic neuropathy by the American Association for Neurology and as a level A recommendation in certain neuropathic states by the European Federation of Neurological Societies. Food and Drug Administration approved duloxetine to treat chronic musculoskeletal pain, including discomfort from osteoarthritis and chronic lower back pain. In 4 clinical trials of duloxetine for the treatment of MDD, sexual dysfunction occurred significantly more frequently in patients treated with duloxetine than those treated with placebo, and this difference occurred only in men.

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Discontinuing an antidepressant medication usually involves cymbalta 60 mg tablet your dose in increments, allowing two to six weeks or longer between dose reductions. Your clinician can instruct you in tapering your dose and prescribe the appropriate dosage pills. In some cases, you can use a pill cutter to create smaller-dose pills, though be sure to check with your clinician or pharmacist to find out if your antidepressant can be cut. Your tapering schedule will depend on which antidepressant you're taking, how long you've been taking it, your current dose, and any symptoms you had during previous medication changes. However, depending on how you respond to each dose reduction, you may want to taper more gradually using smaller dose reductions, longer intervals between dose reductions, or both.

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Duloxetine Cymbalta 30 mg and 60 mg capsules can be prescribed on the Pharmaceutical Benefit Scheme PBS for people with a cymbalta 60 mg tablet depressive disorder. The 30 mg capsule is listed as a month's supply with no repeats. People with renal impairment who require this strength on an ongoing basis will need an authority for any repeats. The PBAC had previously accepted as plausible the argument that the discontinuation rate with duloxetine could be reduced by slower dose titration. However, it remained concerned that in trials twice as many people stopped taking duloxetine because of adverse events as stopped taking venlafaxine. Antidepressants are effective in moderate or severe major depressive disorder.

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What is Cymbalta duloxetine and what is it used for? Other cymbalta 60 mg tablets in this class include milnacipran Savella, venlafaxine Effexor, and desvenlafaxine Pristiq. Cymbalta duloxetine is used for the treatment of depression, generalized anxiety disorder, pain associated with diabetic peripheral neuropathy, fibromyalgia, and chronic musculoskeletal pain. Cymbalta duloxetine affects neurotransmitters, the chemicals that nerves within the brain make and release in order to communicate with one another. Neurotransmitters either travel across the space between nerves and attach to receptors on the surface of nearby nerves or they attach to receptors on the surface of the nerves that produced them, to be taken up by the nerve and released again a process referred to as re-uptake. Many experts believe that an imbalance among neurotransmitters is the cause of depression as well as other psychiatric disorders.

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The rate of discontinuation due to adverse events during the acute phase of the study was The majority of TEAEs were associated with initial duloxetine dosing; further escalations in dose produced few additional adverse events. VAS measures of GI disturbance worsened significantly compared with baseline values after 1 week of duloxetine treatment. During 2 years of extension phase therapy, the rate of discontinuation due buy zantac 150mg adverse events was Mean changes from baseline to the end of the extension phase in supine systolic and diastolic blood pressure were 3.

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