Objectives: The current study was the first pilot study in Iran that compared Haloperidol with Risperidone in the treatment of positive symptoms of psychosis among a group of methamphetamine-dependent patients. Materials and Methods: This randomized clinical trial was designed and conducted in Overall, 44 patients who met the diagnostic and statistical manual of mental disorders, fourth edition-text revised DSM. Patients 1: 1 were randomly divided to two groups. Overall, 22 subjects received Haloperidol 5 - 20 mg and 22 subjects received Risperidone 2 - 8 mg. All subjects were assessed at baseline, during three consecutive weeks of treatment and one week after treatment i. Scale of assessment of positive symptoms SAPS was completed for each subject.

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Pros and cons of this medication, used to treat children with severe behavior problems. Clinical Expert: Michael P. Risperdal is an antipsychotic medication given to kids who have extreme behavior problems like being very aggressive or angry. They might be hurting themselves or others or getting kicked out of school. In some cases it makes the difference between living at home or requiring residential treatment.

Antipsychotic choice for the acute phase of a first episode of psychosis FEP is of the utmost importance since it may influence long-term outcome. The aim of this study was to compare the effectiveness in the short term of aripiprazole and risperidone after FEP outbreak. From February to October, a prospective, randomized, open-label study was undertaken. The primary effectiveness measure was all-cause treatment discontinuation. In addition, an analysis based on intention-to-treat principle was conducted to assess clinical efficacy. The overall dropout rate at 12 weeks was small 6.

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Because these behaviors may be chronic, there is a need to establish the efficacy and safety of longer-term treatment with this agent. Part I consisted of 4-month open-label treatment with risperidone, starting at the established optimal dose; part II was an 8-week randomized, double-blind, placebo-substitution study of risperidone withdrawal. Primary outcome measures were the Aberrant Behavior Checklist irritability subscale and the Clinical Global Impression improvement scale. The mean risperidone dose was 1. The subjects gained an average of 5. Part II included 32 patients.

The chemical designation is 3-ethyl-6,7,8,9-tetrahydromethyl-4H-pyridopyrimidinone. Risperidone is a white to slightly beige powder. Efficacy was established in 4 short-term trials in adults, 2 short-term trials in adolescents ages 13 to 17 years, and one long-term maintenance trial in adults. Efficacy was established in 2 short-term trials in adults and one short-term trial in children and adolescents ages 10 to 17 years. Efficacy was established in one short-term trial in adults. Efficacy was established in 3 short-term trials in children and adolescents ages 5 to 17 years.

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It can cause significant impairment in all areas of functioning in patients of all ages 3. It is important to note that impairment due to ADHD will continue into adulthood and will require treatment 4. The level of impairment of preschoolers with ADHD is similar to that of affected school age children 6. Other problems include preschool expulsion, difficulty in maintaining babysitters or childcare and as a result, missed family work days and personal time 8. This group also had higher rates of emotional adverse effects including lability, crabbiness, irritability, and proneness to crying compared to older children 4 - Also preschool children with ADHD may experience slightly more and different types of stimulant-induced side effects compared with older children 5.

Placebo-treated patients subsequently received an identical open-label trial of risperidone addition. There was no difference in response between OCD patients with and without comorbid diagnoses of chronic tic disorder or schizotypal personalty disorder. Other than mild, transient sedation, risperidone was well tolerated. Conclusion These results suggest that OCD patients with and without comorbid chronic tic disorders or schizotypal personality disorder may respond to the addition of low-dose risperidone to ongoing SRI therapy. Controlled studies of the first approach, adding drugs that further enhance serotonin 5-hydroxytryptamine 5-HT function, such as lithium, 2 buspirone, 3 and clonazepam, 4 have yielded discouraging results. The second approach has involved adding low-dose dopamine antagonists, such as pimozide 5 and haloperidol, 6 to the treatment of SRI-refractory patients.

Cariprazine treatment led to greater improvement in the negative symptoms of schizophrenia than was seen with risperidone, found a recent study. The researchers conducted a randomized, double-blind, phase 3b trial involving 66 hospitals, university clinics, and private practices across 11 countries in Europe. The adults, ages 18 to 65 years, who were enrolled in the study all had stable schizophrenia for at least 2 years, and predominant negative symptoms for at least 6 months. Half the patients received fixed-dose oral cariprazine at 3, 4. Although patients in each group risperdal 4.5 mg the full 26 weeks of treatment, the intent-to-treat analysis included of those in the cariprazine group average 4.

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