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Allopurinol is a purine analogue of hypoxanthine and is a substrate for, and inhibitor of, the enzyme xanthine oxidase. From: Applied Pharmacology, Allopurinol drug interactions have been well characterized. Azathioprine and 6-mercaptopurine 6-MP are metabolized primarily by XO, hence co-administration of allopurinol leads to marked increases in circulating drug levels that can lead to bone marrow suppression. Other allopurinol-associated drug interactions are summarized in Table Although regimens for desensitization have been described, allopurinol should be avoided in patients with known allergies to allopurinol, including AHS.
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Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects. Take this medicine with plenty of liquids to help prevent kidney stones. Check with your doctor about the amount of liquid you should drink each day. You should also increase your fiber intake.
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Free home delivery and Cash on delivery are available. Allopurinol Tablets BP m. Allopurinol Tablets mg are presented as order zyloprim 300, normal convex tablets. International Shipping 2 to 3 weeks transit time to US. Allopurinol is used for the prevention of urate urinary stones by reducing the production of uric acid in your body.
Allopurinol is indicated for the management of recurrent mixed calcium oxalate renal stones in the presence of hyperuricosuria, when fluid, dietary and similar measures have failed. Adults: Allopurinol should be introduced at low dosage e. Extra caution should be exercised if renal function is poor see Patients with renal impairment. Use in children is rarely indicated, except in malignant conditions especially order zyloprim 300 and certain enzyme disorders such as Lesch-Nyhan syndrome. Older people: In the absence of specific data, the lowest dosage which produces satisfactory urate reduction should be used. Particular attention should be paid to advice in patients with renal impairment and section 4.
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Allopurinol is used to treat gout, high levels of uric acid in the body caused by certain cancer medications, and kidney stones. Allopurinol is also sometimes used to treat seizures, pain caused by pancreas disease, and certain infections.
- Allopurinol is used to lower serum and urinary uric acid concentrations in the management of primary and secondary gout.
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- Allopurinol is also used to treat high levels of uric acid that builds up in the blood as tumors break down in people with certain types of cancer who are being treated with chemotherapy medications.
- Generic drugs usually cost less.
- Allopurinol is an inhibitor of xanthine oxidase, a substance in the body that is responsible for producing uric acid.
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Common side effects when used by mouth include itchiness and rash. Allopurinol was approved for medical use in the United States in
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All medicines have risks and benefits. Ask your doctor or pharmacist if you have any concerns about taking this medicine.
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The medication may also be used to treat seizures, infections, and pain caused by pancreas disease.
November 17, 2024
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It is more popular than comparable drugs The typical adult dose of allopurinol for gout is: Initial Dose: to milligrams mg, once a day Maintenance Dose: to mg orally, once a day, for mild gout or to mg a day 3.
March 9, 2023
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