Statins competitively inhibit 3-hydroxymethylglutaryl coenzyme A HMG CoA reductase, an enzyme involved in cholesterol synthesis, especially in the liver. Manufacturer advises if concurrent use of ciclosporin is unavoidable, max. Not licensed for secondary prevention of cardiovascular events. Starting dose of 20 mg once daily is not licensed for the primary prevention of cardiovascular events. Muscle toxicity can occur with all statins, however the likelihood increases with higher doses and in certain patients. Statins should be used with caution in patients at increased risk of muscle toxicity, such as the elderly, those with a personal or family history of muscular disorders, history of muscular toxicity or unexplained persistent muscle pain, history of liver disease, a high alcohol intake, known genetic polymorphisms—consult product literature, renal impairment, or hypothyroidism, or those who undertake strenuous exercise.

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After initiation or upon titration, analyze lipid levels within weeks and adjust dosage accordingly. Indicated as adjunctive therapy to diet to slow the progression of atherosclerosis in adult patients as part of a treatment strategy to lower total cholesterol and LDL cholesterol to target levels. Discontinue treatment if markedly elevated creatine kinase levels occur or myopathy is diagnosed or suspected; temporarily withhold in any patient with an acute, serious condition suggestive of myopathy or predisposing to the development of renal failure secondary to rhabdomyolysis eg, sepsis; hypotension; dehydration; major surgery; trauma; severe metabolic, endocrine, or electrolyte disorders; uncontrolled seizures. Limited data indicate that rosuvastatin is present in human milk; because statins have the potential for serious adverse reactions in nursing infants, women who require rosuvastatin treatment should not breastfeed their infants. SLCO1B1 polymorphism is thought to have a lesser effect on the more hydrophilic statins eg, rosuvastatin, fluvastatin compared with those that are more lipophilic eg, atorvastatin, pravastatin, simvastatin.

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What is rosuvastatin, and how does it work mechanism of action? Rosuvastatin is an oral drug for lowering blood cholesterol levels. These drugs reduce cholesterol levels by inhibiting HMG-CoA reductase, an enzyme that produces cholesterol in the liver. Rosuvastatin and other statins lower blood total crestor 20mg tablet as well as blood LDL cholesterol levels. LDL cholesterol is the bad type of cholesterol that increases the risk of coronary artery disease atherosclerosis and heart attacks. Lowering LDL cholesterol levels slows the progression of coronary artery disease and may even reverse it.

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It belongs to a group of drugs known as statins. Lowering bad cholesterol and triglycerides and raising good cholesterol decreases the risk of heart disease and helps to prevent strokes and heart attacks. Talk with your doctor for more details. Indications: hypercholesterolemia, homozygous familial hypercholesterolemia, heterozygous nortriptyline 2.5 3 mg hypercholesterolemia, hypertriglyceridemia, mixed hyperlipidemia, myocardial infarction prevention, primary dysbetalipoproteinemia, primary prevention of coronary heart disease, prevention of transient ischemic attack, prevention of cerebrovascular accident, atherosclerotic cardiovascular disease, hyperlipidemia. Many people using this medication do not have serious side effects.

Crestor contains rosuvastatin, a cholesterol-lowering medication that is used to treat hypercholesterolaemia by lowering high levels of cholesterol and triglycerides in the blood, which helps reduce risk of heart disease. Crestor tablets 20mg are used to lower high levels of cholesterol hypercholesterolaemia and other fats triglycerides in the blood to reduce health risks associated with coronary heart disease CHD, including heart attack and angina that can be caused by high cholesterol. There are usually no symptoms associated with high cholesterol, which may be due to lifestyle high-fat crestor 20mg tablet and lack of exercise or can be inherited familial hypercholesterolaemia and is not always lifestyle dependent. Crestor tablets 20mg are used in conjunction with a low-fat diet, when lifestyle changes diet and exercise are not sufficient to lower cholesterol in patients with primary hypercholesterolaemia, without clinical evidence of CHD, to reduce risk of CHD and reduce the need for surgery. Crestor tablets 20mg are used to prevent major cardiovascular events heart attack or cerebrovascular events stroke and to prevent the need for coronary artery revascularisation bypass surgery, in those who are at risk of heart attack or stroke and to slow the progression of atherosclerosis hardening of the arteries.

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Rosuvastatin is also taken to lessen the risk of a heart attack or stroke. It works by slowing the production of cholesterol in your body. You should not take rosuvastatin if you are allergic to it, or if you have It could harm the unborn baby. Use effective birth control aspirin tablet 300mg prevent pregnancy while you are taking rosuvastatin.

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Please note Crestor is also available in other strengths Crestor 5mg, 10mg and 40mg Tablets. What is in this leaflet: 1. Atherosclerosis is due to crestor 20mg tablet up of fatty deposits in your arteries. You need to keep taking Crestor, even if it has got your cholesterol to the right level, because it prevents your cholesterol levels from creeping up again and causing build up of fatty deposits. Tell your doctor immediately if you have unexplained muscle aches or pains especially if you feel unwell or have a fever.

Rosuvastatin belongs to a group of medicines known as statins. It regulates the amount of cholesterol and crestor 20mg tablet lipids made by your body, and helps to reduce the risk of heart and blood vessel disease. These also help to reduce the risk of heart and blood vessel disease. Lipids, or fats, are made naturally in your body from the food you eat. Cholesterol and triglycerides are types of lipid. Although a high blood concentration of lipids will not make you feel ill, it can cause a problem if it is left untreated.

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