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Contrast agents are substances that alter, or attenuate, X-rays. The density of a substance determines the degree of attenuation of radiation. Air and gas can be used as contrast agents. They provide negative contrast because they absorb X-rays less than the surrounding tissue. They appear darker on X-ray film and are used to show the outline of surrounding soft tissue.

Renin together with angiotensin-converting enzyme produces angiotensin II, which is a powerful vasoconstrictor and stimulates the release of aldosterone from the adrenal glands. Figure shows the renin-angiotensin-aldosterone pathway. Vasoconstriction and the salt and water reabsorption activity of aldosterone result in restoration of blood volume and therefore blood pressure. In cardiac failure, cardiac output is reduced.

The mode of action remains unknown. Gabapentin is used in buy elavil uk epilepsy together with other drugs that have failed to provide control alone. Adverse effects of gabapentin are gastrointestinal disturbances, mild sedation and ataxia. Topiramate is a recently developed anticonvulsant with similar actions to phenytoin. It appears to block sodium ion channels and enhances the action of GABA.

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Interferon is used to treat chronic hepatitis C infection. Adverse effects of interferon are fever, lethargy, headache and myalgia. AIDS is caused by infection with HIV. It is a virus that causes impairment or deficiency of the immune system.

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