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Nonsteroidal antiinflammatory drugs NSAIDs, including selective cyclooxygenase COX -2 inhibitors, have come to play an important role in the pharmacologic management of arthritis and pain. Clinical trials have established the efficacy of etoricoxib in osteoarthritis, rheumatoid arthritis, acute gouty arthritis, ankylosing spondylitis, low back pain, acute postoperative pain, and primary dysmenorrhea. Etoricoxib was generally well tolerated in these studies with no new safety findings during long-term administration. The gastrointestinal, renovascular, and cardiovascular tolerability profiles of etoricoxib have been evaluated in large patient datasets, and further insight into the cardiovascular tolerability of etoricoxib and diclofenac will be gained from a large ongoing cardiovascular outcomes program MEDAL. The available data suggest that etoricoxib is an efficacious alternative in the management of arthritis and pain, with the potential advantages of convenient once-daily administration and superior gastrointestinal tolerability compared with traditional NSAIDs.

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Each film-coated tablet contains 30, 60, 90 or mg of etoricoxib. There is a further increase in the risk of gastrointestinal adverse effects. To do so we compare two group of patients, randomized, one use the medication etoricoxib and other use placebo and they quantify the pain using the Pain visual analogue scale. Etoricoxib displays improved gastrointestinal safety compared with.

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Distributor: Zuellig Pharma. COX-1 is arcoxia 70mg pill for prostaglandin-mediated normal physiologic functions such as gastric cytoprotection and platelet aggregation. Selective inhibition of COX-2 by etoricoxib decreases these clinical signs and symptoms with decreased GI toxicity and without effects on platelet function.

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Tell your doctor if you have ever had an allergic reaction to any other anti-inflammatory medicine. By blocking the effect of COX-2 enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased. Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking etoricoxib, it is important that your doctor knows

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