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The Online Clinic can prescribe Arcoxia for you if you complete a short online questionnaire about your health background. The active substance in Arcoxia is etoricoxib. NSAIDs do this by inhibiting an enzyme COX involved in prostaglandin production, which facilitates inflammation and pain associated with injuries and some diseases. Arcoxia is taken by mouth, once a day. It can be taken with or without a meal.

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It is particularly effective in treating the pain in arthritis and during a flare up of gout. Etoricoxib eases pain and swelling inflammation in conditions such as osteoarthritis, rheumatoid arthritis and ankylosing spondylitis, and it may also be used for short periods of time in gout, such as duiring a flare up. By blocking the effect of COX-2 enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased. For osteoarthritis: 30 mg once-daily, although the dose can be increased to 60 mg if needed. For rheumatoid arthritis or ankylosing spondylitis: 60 mg once-daily, although the dose can be increased to 90 mg if it becomes necessary.

Nonsteroidal antiinflammatory drugs NSAIDs, including selective cyclooxygenase COX -2 inhibitors, have come to play an important role in the pharmacologic management of arthritis and pain. Clinical trials have established the efficacy of etoricoxib in osteoarthritis, rheumatoid arthritis, acute gouty arthritis, ankylosing spondylitis, low back pain, acute postoperative pain, and primary dysmenorrhea. Etoricoxib was generally well tolerated in these studies with no new safety findings during long-term administration.

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Side effects of thioxanthines are as expected, being antiemetic, Parkinsonism, tardive dyskinesia and raised prolactin levels. This group of anti-psychotic drugs has a similar mode of action and side effects to the phenothiazines. Butyrophenones are of particular use for the rapid control of hyperactive states and in older people because they are less likely to cause a drop in blood pressure. An example is haloperidol.

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