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Zetia is approved to treat these conditions in certain situations. Zetia contains the active drug ezetimibe. Drugs in this class prevent your small intestine from absorbing cholesterol. Zetia comes as a tablet that you swallow. You can take Zetia with or without food. Zetia is a brand-name drug that contains the active drug ezetimibe. This active drug is also available as a generic medication. A generic drug is an exact copy of the active drug in a brand-name medication. The generic is considered to be as safe and effective as the original drug.

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