Repaglinide is used along with diet and exercise in adults with type 2 diabetes. It comes as a tablet you take by mouth. Note: This medication is not used to treat type 1 diabetes or diabetic ketoacidosis DKA. DKA is a life threatening complication of diabetes. The price you pay for repaglinide can vary.

Repaglinide is a potassium channel blocker, which lowers blood glucose by stimulating the release of insulin from the pancreas, used the treatment of type II diabetes. Repaglinide antagonizes the inhibitory action of recoverin in a rhodopsin kinase assay with IC50 values of mM. This is normal and is due to slight batch-to-batch variations. Calculate the mass, volume or concentration required for a solution. Molecular mass molecular weight is the mass of one molecule of a substance and is expressed in the unified atomic mass units u. Answers to questions you may have can be found in the inhibitor handling instructions.

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The 1 mg and 2 mg tablets contain iron oxides yellow and red, respectively as coloring agents. PRANDIN is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. The recommended dose range is 0. At least one week should elapse to assess response after each dose adjustment. Gradually titrate the dose, if needed to achieve glycemic control. Both patients had a prior history of coronary artery disease and recovered after treatment with diuretic agents. Less common adverse clinical or laboratory events observed in clinical trials included elevated liver enzymes, thrombocytopenia, leukopenia, and anaphylactoid reactions. Clopidogrel Clinical Impact: Clopidogrel increased repaglinide exposures by 3. Increased frequency of glucose monitoring may be required during concomitant use. Cyclosporine Clinical Impact: Cyclosporine increased low dose repaglinide exposures by 2.

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Diabetes mellitus, type 2, treatment Meglitinides are associated with a greater risk of hypoglycemia than other noninsulin antidiabetic agents Ref. The renal dosing recommendations are based upon the best available evidence and clinical expertise. Hemodialysis, intermittent thrice weekly: Not dialyzable Ref Peritoneal dialysis: Unlikely to be dialyzed highly protein bound Ref There are no dosage adjustments provided in the manufacturer's labeling.

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Repaglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus NIDDM. Repaglinide induces an early insulin response to meals decreasing postprandial blood glucose levels. It should only be taken price of prandin meals and meal-time doses should be skipped with any skipped meal. Approximately one month of therapy is required before a decrease in fasting blood glucose is seen. Meglitnides may have a neutral effect on weight or cause a slight increase in weight. Due to their mechanism of action, meglitinides may cause hypoglycemia although the risk is thought to be lower than that of sulfonylureas since their action is dependent on the presence of glucose.

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