Tell your doctor if you are currently taking simvastatin or products containing simvastatin. Tell your doctor about all your medical conditions, including history of heart disease or liver problems. You may experience symptoms of low blood pressure dizziness, lightheadedness if you have heart diseases. The most common side effects of NORVASC include swelling of your legs or ankles, dizziness, flushing hot or warm feeling in your face, and heart palpitations very fast heartbeat. Other side effects include fatigue, nausea, stomach pain, or extreme sleepiness.

Objectives Hypertension is well established as a major risk factor for cardiovascular disease. Research into the treatment of hypertension has produced a multitude of drug classes with different efficacy profiles. One of the oldest groups of antihypertensives, the calcium channel blockers are a heterogeneous group of medications. Results Amlodipine has good efficacy and safety, in addition to strong evidence from large randomised controlled trials for cardiovascular event reduction. Conclusions Amlodipine should be considered a first-line antihypertensive agent. It is well known that many antihypertensive medications reduce the risk of stroke and heart attack.

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Caused by decreased compliance of large arteries, systolic hypertension is an independent risk factor for cardiovascular disease. Recent studies have demonstrated that it is more important to control systolic blood pressure SBP than diastolic blood pressure DBP. Of citations identified, 85 primary studies met all inclusion criteria. Comparable treatment arms were pooled, and weightd mean SBP was calculated. The median daily dose was 5 mg range, 1. Antihypertensive agents such as amlodipine warrant consideration for the management of patients with inadequately controlled SBP.

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It explains how the Agency assessed the medicine to recommend its authorisation in the EU and its conditions of use. One tablet is taken daily by mouth with water. It is recommended that the patient takes amlodipine and valsartan as separate tablets or capsules before switching to the combination tablet. The strength of the tablet to be used depends on the doses of amlodipine or valsartan that the patient was taking before. Both are anti—hypertensive medicines that have been available separately in the European Union EU since the mids.

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Amlodipine is a commonly used vasodilator for the management of cardiovascular conditions such as hypertension, angina. We present a case of amlodipine toxicity causing intractable acidosis, cardiovascular decompensation and eventual death. A year-old Caucasian male with past medical history of hypertension presented to our hospital after an intentional overdose of 50 mg tablets of amlodipine total of mg and a self-inflicted abdominal knife wound in an apparent suicide attempt. Pertinent physical examination findings included a superficial knife wound in the left lower abdominal quadrant, non-reactive pupils, cool extremities and bilateral rhonchi and rales. The rest of the physical examination was negative. A CT scan with contrast of the abdomen and pelvis revealed that the knife wound did not penetrate the peritoneum and the patient was cleared from a trauma perspective.

Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including Norvasc. Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than one drug to achieve blood pressure goals. The largest and most consistent cardiovascular outcome benefit has been a reduction in the risk of stroke, but reductions in myocardial infarction and cardiovascular mortality also have been seen regularly. Elevated systolic or diastolic pressure causes increased cardiovascular risk, and the absolute risk increase per mmHg is greater at higher blood pressures, so that even modest reductions of severe hypertension can provide substantial benefit.

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If you're not sure, check with your norvasc 15 mg again or your pharmacist. Amlodipine comes as 5mg and 10mg tablets. The liquid comes as 2 different strengths, one with 5mg amlodipine in 5ml and one with 10mg in 5ml. If the starting dose is not working well enough for example, your blood pressure does not get any lower, or your angina is not controlled, your dose may need to be increased to 10mg. To decide the correct dose for you in the longer term, your doctor will check your blood pressure to make sure it's not too high or too low.

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They influence the myocardial cells, the cells within the specialised conducting system of the heart, and norvasc 15 mg cells of vascular smooth muscle. Tablets from various suppliers may contain different salts e. Amlodipine has been confused with nimodipine and atenolol; care must be taken to ensure the correct drug is prescribed and dispensed. See also Prescribing in the elderly. Abdominal pain; dizziness; drowsiness; flushing; headache; nausea; palpitations; peripheral oedema; skin reactions; tachycardia; vomiting.

When you first start taking amlodipine you may get a headache, or feel flushed and hot. These symptoms tend to go after the first few days. Amlodipine is given to treat high blood pressure hypertension. It is also taken to help prevent angina chest norvasc 15 mg. You may have been prescribed it for either of these reasons.

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