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Linezolid is also a reversible, non-selective inhibitor of monoamine oxidase, which can increase levels of dopamine, noradrenaline and serotonin. This can increase the chance of certain adverse effects and food and drug interactions. Linezolid can cause serious toxicity including myelosuppression, lactic acidosis, neuropathy peripheral and optic and order zyvox syndrome when co-prescribed with serotonergic agents. If linezolid is recommended for a patient by an infection specialist, this protocol should be used to ensure that appropriate checks and monitoring are undertaken to reduce patient risk. Discharge and Outpatient Supply Checklist For ALL patients discharged on, or prescribed linezolid via an outpatient clinic, the prescriber will need to complete a Checklist.

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