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At Interlude, our goal is to make our pricing as easy and comfortable as the care we offer. These changes are also known as vulvovaginal atrophy or the genitourinary syndrome of menopause GSM. Estradiol vaginal cream helps prevent vaginal and urinary discomfort due to menopause genitourinary syndrome of menopause. The North American Menopause Society stated in For bothersome genitourinary syndrome of menopause symptoms not relieved with over-the-counter therapies in women without indications for use of systemic hormone therapy, low-dose vaginal estrogen therapy or other therapies eg, vaginal dehydroepiandrosterone are recommended. The vulva, vagina, urethra, labia, bladder, and sexual organs are tissues in the body that exist because they contain estrogen.

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