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The mechanism of action is not fully understood, but nitrofurazone's antimicrobial properties are suspected to be due to the interference of DNA synthesis in the microorganism by inhibiting certain enzymes that are involved with glycolysis. Rapid absorption of the medication induces increased serum osmolalities and anion gap, leading to death. Nitrofurans have been found in honey, meat and seafood. In people who have glucosephosphate dehydrogenase deficiency GPD deficiency, ingestion of fish, poultry, or other foodstuff that has been treated with nitrofurans, will likely suffer from hemolysis of red blood cells as a result of eating the contaminated food. Nitrofurazone is suspected to be a human carcinogen and is included in California's list of toxic chemicals as defined by Proposition From Wikipedia, the free encyclopedia. Office of Environmental Health Hazard Assessment. National Institute of Health: 1— Minimally Invasive Neurosurgery Clinic.

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