Sertraline may be taken with or without food. The dose your healthcare provider recommends will vary, depending on the medical condition being treated and other. I decided I had taken the drug for too long. The risk of blood pressure decreases may be greater when duloxetine the active ingredient contained in Cymbalta is given concomitantly with drugs that may induce orthostatic hypotension, such as antihypertensives, with potent CYP 1A2 inhibitors, or with duloxetine doses above 60 mg per day The recommended dose for PMDD is 50 to mg every day of the menstrual cycle or for 14 days before menstruation. Children—Use and dose must be determined by your doctor. My doctor told me to take 1 capsule every other day for 2 weeks, then 1 capsule 3 times a week for 1 week. Duloxetine only comes as a capsule you take by mouth.

In addition to depression, doctors can prescribe Cymbalta to treat anxiety that lasts for at least six months, pain from diabetic nerve damage, fibromyalgia, and long-term muscle or bone pain. It works by increasing the levels of the neurotransmitters serotonin and norepinephrine, which help regulate mood and may block pain signals traveling through the brain. The researchers noted that use of Cymbalta could result in fewer side effects than the drugs traditionally used for the condition, such as non-steroidal anti-inflammatory drugs, or NSAIDs, which can lead to gastrointestinal bleeding, and opioids like, which often lead to constipation. They concluded that doctors may consider adding antidepressants, such as Cymbalta to the treatment regimens for patients with osteoarthritis. The FDA requires that Cymbalta carry a black-box warning about the risk of suicide among people who use the antidepressant.

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Cymbalta is an antidepressant approved to treat mood and pain disorders. It works by preventing the body from reabsorbing two neurotransmitters: serotonin and norepinephrine. The drug has a long list of interactions, and possible side effects include nausea, increased sweating and withdrawal symptoms. Eli Lilly and Company manufactures the medication. Food and Drug Administration first approved the antidepressant in The drug quickly grew in popularity. The FDA originally approved Cymbalta for major depressive disorder and generalized anxiety disorder. The agency has since approved the medication for diabetic peripheral neuropathic pain, fibromyalgia and chronic musculoskeletal pain in adults. The drug is not approved for use in children and teens.

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Duloxetine Cymbalta 30 mg and 60 mg capsules can be prescribed on the Pharmaceutical Benefit Scheme PBS for people with a major depressive disorder. The 30 mg capsule is listed as a month's supply with no repeats. People with renal impairment cheap ddavp require this strength on an ongoing basis will need an authority for any repeats. The PBAC had previously accepted as plausible the argument that the discontinuation rate with duloxetine could be reduced by slower dose titration. However, it remained concerned that in trials twice as many people stopped taking duloxetine because of adverse events as stopped taking venlafaxine. Antidepressants are effective in moderate or severe major depressive disorder.

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You may also be prescribed generic duloxetine capsules; 30 mg and 60 mg capsules are prescribed for mood and nerve disorders. Ask your pharmacist if you have any questions or concerns. Please tell your doctor if you feel that you are getting worse, or if you experience any troublesome side-effects. Duloxetine can make you feel dizzy or sleepy. If this happens, do not drive and do not use tools or machines.

The starting and recommended maintenance dose is 60 mg once daily with or without food. Dosages above 60 mg once daily, up to a maximum dose of mg per day have been evaluated from a safety perspective in clinical trials. However, there is no clinical evidence suggesting that patients not responding to the initial recommended dose may benefit from dose up-titrations. After consolidation of the antidepressive response, it is recommended to continue treatment for several months, in order to avoid relapse. The recommended starting dose in patients with generalised anxiety disorder is 30 mg once daily with or without food. In patients with insufficient response the dose should be increased to 60 mg, which is the usual maintenance dose in most patients.

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Do not take duloxetine within 5 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. Some young people have thoughts about suicide when first taking an antidepressant. Duloxetine is also used to treat fibromyalgia a chronic pain disorder in adults and children at least 13 years old. Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Symptom improvement began within the first few weeks, and continued for the duration of the studies. Duloxetine was noninferior compared with venlafaxine XR. Duloxetine was found to have a good tolerability profile which was predictable and similar to another SNRI, venlafaxine. Adverse events AEs such as nausea, constipation, dry mouth, and insomnia were mild and transient, and occurred at relatively low rates. It was found to have a low frequency of drug interactions.

People with depression or mental illness may have thoughts about suicide. Tell your doctor right away if you have any sudden changes in mood or behavior, or thoughts about suicide. Duloxetine is used to treat major depressive disorder in adults. Duloxetine is also used to treat general anxiety disorder in adults and children at least 7 years old. Some brands of duloxetine are also used to treat fibromyalgia a chronic pain disorder.

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