UK, remember your settings and improve government services. Sets out medicines that cannot be exported from the UK or hoarded because they are needed for UK patients. This document lists the medicines that cannot be exported from the UK or hoarded. The government has produced guidance on export and hoarding of restricted medicines. In October, a letter to holders of a wholesale dealer licence was sent out about the restrictions on parallel exports. Check the guidance on the exhaustion of Intellectual Property rights and parallel trade. Hoarding or exporting a medicine on the list is considered a breach of regulation 43 2 of the Human Medicines Regulations and a contravention of the wholesale dealer licence and may lead to regulatory action by the Medicines and Healthcare products Regulatory Agency MHRA, which could include immediate suspension of the wholesale dealer licence.

Ernst, clinical professor at the University of Iowa College of Pharmacy and researcher on blood pressure variability, told Healthline. Therefore, they are not usually used as a monotherapy, but are usually reserved for adding to other antihypertensives when the existing regimen fails to achieve the goal blood pressure. Prior research from revealed a link between large variations in blood pressure and increased mortality risk. Then, during the American College of Cardiology Scientific Session, researchers warned that alpha-blockers and alpha-2 agonists were more associated with blood pressure variability than other commonly used medications. According to researchers, that variation in blood pressure was linked to an increased risk of death. The researchers recorded both blood pressure variation as well as the blood pressure medication used by each participant. The study authors advocated for physicians to prescribe other blood pressure medications to decrease mortality risk for their patients.

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