Depot medications can improve treatment adherence 2 ; however, long-term antipsychotic use can lead to irreversible adverse effects dyskinesias, which in some cases were reduced by using newer antipsychotics. Aripiprazole was developed based on the dopamine theory, in which dopamine hyperactivity in mesolimbic pathways of the brain leads to hallucinations, delusions, disorganization, and catatonia, and dopamine hypoactivity in mesocortical pathways and the prefrontal cortex causes alogia, anhedonia, autism, avolition, and problems with attention and abstract thinking. Metabolism through CYP2D6 and 3A4 enzymes predisposes aripiprazole to drug-drug interactions, which may require dose adjustment. After depot aripiprazole is injected into the gluteal muscle, the active moiety slowly is released into circulation. The effectiveness of depot aripiprazole is attributable to its active parent drug, aripiprazole monohydrate, and its active metabolite, dehydro-aripiprazole, which is the same as oral aripiprazole.

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Manufacturer: Otsuka Philippines. Aripiprazole Abilify Maintena aripiprazole is an extended-release injectable suspension available in mg or mg strength pre-filled dual chamber syringes. Pharmacology: Mechanism of Action: The mechanism of action of aripiprazole in the treatment of schizophrenia and bipolar I disorder is unknown. The efficacy of aripiprazole could be mediated through a combination of partial agonist activity at dopamine D 2 and serotonin 5-HT 1A receptors and antagonist activity at 5-HT 2A receptors. Pharmacodynamics: Aripiprazole exhibits high affinity for dopamine D 2 and D 3, K i s 0.

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This summary is based on data available to December Deltoid initiation Deltoid or gluteal maintenance.

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After you swallow the tablet, the sensor sends a signal to a patch worn on your belly. The abilify maintena cost connects to an app on your smartphone. This sensor is made of natural ingredients and breaks down in your body after you take the tablet. An active ingredient is what makes a drug work. Note: For more details on Abilify, see this in-depth article. The price you pay for Abilify can vary.

The best pharmacy offers for Abilify Uses. What is the abilify maintena cost of Abilify Maintena? Abilify Maintena aripiprazole pre-fill ed dual chamber syringe for extended-release injectable suspension in single-use syringes is available in mg or mg strength syringes. Abilify Maintena does not contain lactose, gluten, sucrose, tartrazine or any other azo dyes. Do not take this medicine if you are allergic to any of these ingredients. What Abilify Maintena looks like.

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