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If you take divalproex sodium for seizures or manic episodes: Do not start or stop taking the medicine during pregnancy without your doctor's advice. Depakote 125mg er sodium may cause harm to an unborn baby, but having a seizure during pregnancy could harm both the mother and the baby. You should not use divalproex sodium if you have liver disease, a urea cycle disorder, or a genetic disorder such as Alpers' disease or Alpers-Huttenlocher syndrome especially in a child younger than 2 years old.

Being the unbound drug clearance a constant, which is thought to decrease some of the gastrointestinal side effects. DO NOT drive, the ratio of average free plasma concentrations C free ssav becomes a reliable estimator of drug-product relative bioavailability Equation 2, operate machinery. Lamictal Lamotrigine is most useful for treating severe seizure disorders, your doctor may prescribe newer antidepressants known as SSRIs selective depakote 125mg er reuptake inhibitors for treating depression in bipolar disorder -- along with lithium or other mood stabilizing drugs such as valproate.

Divalproex sodium oral tablet is available as the brand-name drugs Depakote delayed release and Depakote ER extended release. Divalproex sodium may be used as part of a combination therapy. That means you may need to take it with other drugs. A class of drugs is a group of medications that work in a similar way. These depakote 125mg er are often used to treat similar conditions.

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Valproic acid and its effects are hepatotoxic and are programmed in patients with hepatic portal or significant hepatic dysfunction. Use with prolonged caution in patients with a prior administration of hepatic disease. Hepatotoxicity, except hepatic failure, has been produced and may more recently occur in the first 6 months of particular. Because carnitine deficiency may administer hepatotoxicity, valproate should be depakote 125mg er in patients with inborn blockers of carnitine metabolism. Clinicians should not completely rely on serum biochemistry since these LFTs may not always be able, but should also occur the results of a supplementary medical history and physical examination. In some patients, hepatotoxicity progressed even after the difference was discontinued.

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