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Oxybutynin transdermal patches are used to treat an overactive bladder a condition in which the bladder muscles contract uncontrollably and cause frequent urination, urgent need to urinate, and inability to control urination. It is usually applied twice each week every 3—4 days.
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Oxybutynin, via an anticholinergic effect, relaxes the detrusor oxytrol cost of the bladder. The patch avoids first-pass metabolism in the liver, reducing the active metabolite N-desethyloxybutynin, the main cause of dry mouth. Oxtybutynin should not be used in patients with urinary retention, gastric retention, or uncontrolled angle-closure glaucoma. Dry mouth is the most common complaint with the oral anticholinergic drugs oxybutynin and tolterodine. Another study compared transdermal oxybutynin with extended-release oral tolterodine, and found a similar rate of dry mouth 4.

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