Prochlorperazine suppository is used to control severe nausea and vomiting. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. Use in children younger than 2 years of age or weighing under 9 kg 20 lbs is not recommended.

There is no such thing as a hangover cure. Mikhail Varshavski, a board-certified family-medicine doctor in New York City a. And though there is some science to back up the claims of these hangover remedies, with so many options on the market, it can be hard to know which of these hangover cures is the right fit for you — and which ones will do the least damage. Treating Hangovers Since: the s. Preventative or Palliative? Directions: Those who swear by activated charcoal as a hangover remedy will often take two capsules before drinking. Hangover-Busting Ingredient: activated charcoal.

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Prochlorperazine is a drug used to treat severe nausea and vomiting. Prochlorperazine overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose. DO NOT use it to treat or manage an actual overdose. This national hotline will let you talk to experts in poisoning. They will give you further instructions.

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Analyses of 17 placebo-controlled trials modal duration of 10 weeks, largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients between 1. Over the course of a typical week controlled trial, the rate of death in drug-treated patients was approximately 4. Although the causes of death were varied, most of the deaths appeared to be either cardiovascular eg, heart failure, sudden death or infectious eg, pneumonia in nature. The extent to which the findings of increased mortality in observational studies may be attributed to the antipsychotic drug as opposed to some characteristic s of the patients is not clear. Chemotherapy-induced nausea and vomiting off-label use IV, Oral: 5 to 10 mg once prior to chemotherapy Ref.

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Compazine suppository cost Prochlorperazine is the most commonly used antiemetic in this class; it is moderately effective for nausea caused. Buying Compazine Prochlorperazine 9. Some health conditions may make you more susceptible to the side-effects of the drug. In, the French physician Prosper Meniere described a condition which now bears his name. Meniere's disease is a disorder of the inner ear which causes episodes of vertigo, ringing or roaring in the ears tinnitus, a feeling of fullness or pressure in the ear, and fluctuating hearing loss.

An understanding of the pathophysiology of nausea and the mechanisms of antiemetics can help family physicians improve the cost-effectiveness and efficacy of therapy. Nausea and vomiting are mediated primarily by visceral stimulation through dopamine and serotonin, by vestibular and central nervous system causes through histamine and acetylcholine, and by chemoreceptor trigger zone stimulation through dopamine and serotonin. Treatment is directed at these pathways. Antihistamines and anticholinergic agents are most effective in patients with nausea resulting from vestibular and central nervous system causes. Dopamine antagonists block dopamine in the intestines and chemoreceptor trigger zone; indications for these agents are similar to those for serotonin antagonists.

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