It is used in the treatment of Schizophrenia. Schizophrenia is a serious mental disorder in which people interpret reality abnormally. The symptoms may include hallucinations, delusions, and extremely disordered thinking and behaviour that impairs daily functioning and can be disabling. Along with this treatment, your doctor might ask you to make certain lifestyle changes, such as eating a healthy diet, regular exercise and quitting alcohol. Consult your doctor before receiving.

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Olanzapine long-acting injection will be given to you by your clinic doctor or nurse every weeks. There are a number of side-effects which you could experience from the treatment. If you are concerned about any, you should discuss them with your doctor. You will have been prescribed it to maintain symptom control of schizophrenia. Schizophrenia is a mental health condition that causes disordered ideas, beliefs and experiences. Symptoms of schizophrenia include hearing, seeing, or sensing things that are not real, having mistaken beliefs, feeling unusually suspicious, and becoming withdrawn. Olanzapine is used to relieve the symptoms of schizophrenia and other similar mental health problems. It works on the balance of chemical substances in your brain. Long-acting, or 'depot', injections are used once your symptoms have been eased by taking tablets.

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WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. Olanzapine injection is an atypical antipsychotic that is FDA approved for the treatment of acute agitation associated with schizophrenia and bipolar I mania. Common adverse reactions include orthostatic hypotension, peripheral edema, hypercholesterolemia, Hyperglycemia, hyperprolactinemia, Increased appetite, serum triglycerides raised, weight increased, constipation, xerostomia, akathisia, asthenia, dizziness, somnolence, tremor, personality disorder. The efficacy of intramuscular olanzapine for injection in controlling agitation in these disorders was demonstrated in a dose range of 2.

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To treat acute schizophrenia, a long-acting injectable antipsychotic needs a rapid onset of action and therapeutic profile similar to that of oral agents. The present post-hoc analyses compared results from a randomized, double-blind, placebo-controlled trial of olanzapine long-acting injection LAI for acute schizophrenia with those observed in similarly designed trials of oral olanzapine. Six-week effect sizes were calculated. Efficacy onset, pharmacokinetics, discontinuations, weight gain, and extrapyramidal symptoms were also assessed. For those 300 mg olanzapine dose groups, effect sizes vs. Olanzapine concentrations were similar across studies.

Each vial contains olanzapine pamoate monohydrate equivalent to mg olanzapine. After reconstitution each ml of suspension contains mg olanzapine. Maintenance treatment of adult patients with schizophrenia sufficiently stabilised during acute treatment with oral olanzapine. ZYPADHERA mg, mg, and mg, powder and solvent for prolonged release suspension for injection must not be confused with olanzapine 10 mg powder for solution for injection. 300 mg olanzapine oral olanzapine dose.

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Olanzapine long-acting injection OLAI is a sustained-release depot antipsychotic for the treatment of schizophrenia in adults. Our objective was to explain the pharmacokinetics of OLAI to provide clinical insight. Simulation models and data from clinical trials are presented. Olanzapine concentrations were observed immediately upon injection. Peak concentrations most often occurred at 2—4 days after injection. Peak-to-trough fluctuation was greater for the 4-week dosing interval than the 2-week 300 mg olanzapine, with no apparent clinical ramifications for these differences.

Use: Treatment of schizophrenia. Use: For the treatment of treatment-resistant depression major depressive disorder in patients who do not respond to 2 separate trials of different antidepressants of adequate dose and duration in the current episode based on clinical studies. Use: For the treatment of acute agitation associated with schizophrenia and bipolar I mania. Oral: 13 to 17 years Initial dose: 300 mg olanzapine. Uses Acute treatment of manic or mixed episodes associated with bipolar I disorder and maintenance treatment of bipolar I disorder -Treatment of depressive episodes associated with bipolar I disorder when used in combination with fluoxetine.

Sections without translation will be in English. To evaluate the efficacy and safety of different doses of olanzapine for people with schizophrenia. Schizophrenia is a complex and severe mental illness that has a significant impact on individuals and their families Owen It usually starts in early 300 mg olanzapine and in rare cases, during childhood or old age. Slightly more men are diagnosed with schizophrenia than women and women tend to have a later onset Abel

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