Norvasc Capsules Hard Gelatin. Oral Prinzmetal's angina; Stable angina Adult: Initially, 5 mg once daily increased to 10 mg once daily if necessary. Hypertension Adult: Initially, 5 mg once daily increased to 10 mg once daily if necessary. May be taken with or without food. Hypersensitivity to Amlodipine or other calcium channel antagonist, Severe hypertension. Impaired liver or renal function, CHF, sick-sinus syndrome, severe ventricular dysfunction, hypertrophic cardiomyopathy, severe aortic stenosis. Caution when used in patients with idiopathic hypertrophic subaortic stenosis.

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Objectives Hypertension is well established as a major risk factor for cardiovascular disease. Research into the treatment of hypertension has produced a multitude of drug classes with different efficacy profiles. One of the oldest groups of antihypertensives, the calcium channel blockers are a heterogeneous group of medications. Results Amlodipine has good efficacy and safety, in addition to strong evidence from large randomised controlled trials for cardiovascular event reduction. Conclusions Amlodipine should be considered a first-line antihypertensive agent. It is well known that many antihypertensive medications reduce the risk of stroke and heart attack.

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For both hypertension and angina the usual initial dose is 5 mg amlodipine once daily which may be increased to a maximum dose of 10 mg depending on the individual patient's response. In hypertensive patients, Amlodipine has been used in combination with a thiazide diuretic, Alpha blocker, beta blockers, or an angiotensin-converting enzyme inhibitors, No dose adjustment of Amlodipine is required upon concomitant administration of thiazide diuretics, beta blockers, and angiotensin-converting enzyme inhibitors. The recommended antihypertensive oral dose in pediatric patients ages years is 2. Doses in excess of 5 mg daily have not been studied in pediatric patients see section 5. Amlodipine, used at similar doses in elderly or younger patients, is equally well tolerated.

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How Amlodipine works Amlodipine is a calcium channel blocker. In high blood pressure, it normalizes the blood pressure by relaxing the blood vessels to reduce the pressure on them, thereby improving the blood flow in the body. The enhanced blood flow in the body, further relaxes the heart muscles by reducing the workload on the heart. Common side effects of Amlodipine Headache, Nausea, Abdominal pain, Flushing sense of warmth in the face, ears, neck and trunk, Dizziness, Palpitations, Edema swelling, Muscle cramp, Visual disturbance, Shortness of breath, Change in bowel habits, Weakness. Stamlo Dr Reddy's Laboratories Ltd.

Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities than other calcium channel blockers 5. Amlodipine is commonly used in the treatment of high blood pressure and angina. Amlodipine has antioxidant properties and crestor rosuvastatin 5mg ability to enhance the production of nitric oxide NO, an important vasodilator that decreases blood pressure 3. The option for single daily dosing of amlodipine is an attractive feature of this drug Label. A governmentally-recognized ID which uniquely identifies the product within its regulatory market. Amlodipine has a strong affinity for cell membranes, modulating calcium influx by inhibiting selected membrane calcium channels.

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Explore nursing assessments, interventions, rationales, teaching strategies, and goals to effectively manage HTN. Hypertension is the norvasc 2 5 mg used to describe high blood pressure. Hypertension is repeatedly elevated blood pressure exceeding over 90 mmHg. Blood pressure is determined by the interaction of cardiac output and peripheral resistance. Hypertension can result from increased cardiac output, increased peripheral resistance, or both.

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