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You should not take alendronate if you have low levels of calcium in your blood hypocalcemia, or a problem with the movement of muscles in your esophagus. Do not take an alendronate tablet if you cannot sit upright or stand for at least 30 minutes after taking the medicine. Alendronate slows bone loss while increasing bone mass, which may prevent bone fractures. Alendronate is used in men and women to treat or prevent osteoporosis that is caused by menopause or by taking steroids. You should not take alendronate if you are allergic to it, or if you have low levels of calcium in your blood hypocalcemia, or a problem with the movement of muscles in your esophagus. Do not take an alendronate tablet if you cannot sit upright or stand for at least 30 minutes. Alendronate can cause serious problems in the stomach or esophagus the tube that connects your mouth and stomach.

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You should not take alendronate if you have problems with your esophagus, or low levels of calcium in your blood. Do not take alendronate if you cannot sit upright or stand for at least 30 minutes after taking the medicine. Alendronate can cause serious problems in the stomach or esophagus. Alendronate is used to treat osteoporosis caused by menopause, steroid use, or gonadal failure. This medicine is for use when you have a high risk of bone fracture due to osteoporosis. Do not take alendronate if you cannot sit upright or stand for at least 30 minutes.

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Alendronate is used to prevent and treat osteoporosis thinning of the bone in women after menopause. This medicine may also be used to increase bone mass in men who have osteoporosis, and in men and women to prevent and treat osteoporosis caused by long-term use of corticosteroids cortisone-like medicine. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals.

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To evaluate the effect of alendronate on bone mineral density in chronic spinal cord injury SCI patients. A fosamax 20 mg of 19 chronic SCI patients were evaluated, divided into a control group and an experimental group. The study duration was 6 months. In all, 12 densitometric parameters were analysed using whole-body dual-energy X-ray absorptiometry at baseline and after 6 months. The experimental group presented increases in nine densitometric parameters, although statistical significance was attained in only two of those parameters.

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In postmenopausal women, Fosamax increases bone mass and reduces the incidence of fractures, including those of the hip and spine vertebral compression fractures. Fosamax is indicated for the prevention of postmenopausal osteoporosis. In patients with these conditions, serum calcium and symptoms of hypocalcemia should be monitored during therapy with Fosamax. This category of drugs includes Fosamax alendronate. In placebo-controlled clinical fosamax 20 mg of Fosamax, the percentages of patients with these symptoms were similar in the Fosamax and placebo groups. The risk versus benefit of Fosamax for treatment at daily dosages of glucocorticoids less than 7.

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Bisphosphonates inhibit bone resorption with relatively few side effects. As a result, they are widely used to prevent osteoporotic fractures. Lifestyle measures — Lifestyle measures include adequate calcium and vitamin D, exercise, smoking cessation, counseling on fall prevention, and avoidance of heavy alcohol use. These measures should be adopted universally to reduce bone loss in people with osteoporosis. Pharmacologic therapy — In addition to lifestyle measures, patients at high risk for fracture should receive pharmacologic therapy.

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Our experts will discuss how both men and women are affected by this metabolic bone disease. They will address early detection and prevention strategies that focus on balance and falls, vitamin D intake and the amount of calcium in your diet, along with the variety of osteoporosis medications available.

  • It treats osteoporosis in postmenopausal women and men at high risk of fractures.
  • Alendronate sodium is a bisphosphonate that acts as a specific inhibitor of osteoclast -mediated bone resorption.
  • Renal transplant patients often have severe bone and mineral deficiencies.
  • At trial, Merck presented evidence that it acted responsibly in researching and developing FOSAMAX and in monitoring the medicine since it has been on the market.

It reduces the risk of vertebral and hip fractures. Therefore no dosage adjustment is necessary for the elderly.

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Osteoporosis is commonly seen in aged people, but not much attention is paid to it. Patient compliance is challenged by many factors, including long-time treatment and high rates of fatality and disability caused by fragility fractures.

Alendronate belongs to a family of medications known as bisphosphonates. It is used to treat and prevent osteoporosis for postmenopausal fosamax 20 mg. It is also used to treat osteoporosis for men. Alendronate may also be used to treat and prevent steroid-induced osteoporosis for men and women osteoporosis caused by taking corticosteroids such as prednisone for long periods of time. Alendronate increases the thickness of bone bone mineral density by slowing down the cells that usually break down bone osteoclasts.

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Alendronate is also available in combination with cholecalciferol vitamin D 3. Balance characteristics of persons with osteoporosis. Evaluating bone mineral density in osteoporosis. Selecting patients for osteoporosis therapy. Cost-effectiveness of different screening strategies for osteoporosis in postmenopausal women. The pathogenesis, diagnosis, investigation and management of osteoporosis.


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This illustrates the model fitted to fracture outcomes exemplified by hip fracture using alendronate sodium refill compliance medication possession ratio MPR as the time-dependent covariate.

January 4, 2024
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