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Levaquin is a synthetic antibiotic of the fluoroquinolones group, which has a wide spectrum of antimicrobial activity. The advantages of Levaquin include high efficiency in the treatment of lower respiratory tract infections and a good safety profile. The active substance of Levaquin is the antimicrobial agent Levofloxacin, which was synthesized and developed at the end of the last century in Japan.

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The second case study is a patient who could be seen by any health care professional. The use of drugs to eradicate micro-organisms and parasitic worms in the body is called chemotherapy. Drugs that are used to treat infections with micro-organisms are known as antimicrobial drugs or antibiotics.

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Distribution of drugs around the body is likely to be different in older people because of changes in body composition, plasma protein concentration and blood flow to major organs. With ageing, body composition changes such that there is more body fat with respect to total body weight, and the proportion of body water falls. The importance of this is that highly lipid-soluble drugs, for example benzodiazepines, tend to have prolonged duration of action.

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