Dosing convenience is a key element in the effective management of any chronic disease, and is particularly important in the long-term management of osteoporosis. Less frequent dosing with any medication may enhance compliance, thereby maximizing the effectiveness of therapy. In addition, dog studies suggest that the potential for esophageal irritation, observed with daily oral bisphosphonates, may be substantially reduced with once-weekly dosing. This dosing regimen would provide patients with increased convenience and would be likely to enhance patient compliance. The primary efficacy endpoint was the comparability of increases in lumbar spine BMD, using strict pre-defined equivalence criteria.

Supplement calcium and vitamin D if dietary intake is inadequate. The optimal treatment duration has not been determined; reevaluate treatment on a periodic basis. For those patients at low risk for fracture, consider stopping alendronate after 3 to 5 years. Bisphosphonates are a first-line therapy for the treatment of osteoporosis in postmenopausal women; alendronate is additionally effective in men with osteoporosis. For postmenopausal women who are not taking estrogen hormonal replacement, the dose is 10 mg PO daily. For use in patients taking systemic corticosteroids i. Retreatment may be considered after a 6-month post-treatment evaluation period, based on increases in serum alkaline phosphatase.

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Treatment of postmenopausal osteoporosis. Treatment of osteoporosis in men. Limitations of use: alone should not be used to treat vitamin D deficiency. Optimal duration of use has not been determined. For patients at low-risk for fracture, consider drug discontinuation after 3—5yrs. Take in the AM with plain not mineral water only, at least 30 mins before the first food, drink, or medication of the day 6—8oz water after tabs or 2oz after oral solution ; do not lie down for at least 30 mins and until after the first food of the day. Osteoporosis prevention in postmenopausal women: 5mg tab once daily or 35mg tab once weekly. Glucocorticoid-induced: 5mg tab once daily; glucocorticoid-induced in postmenopausal women not on estrogen: 10mg tab once daily. Esophageal abnormalities which delay esophageal emptying eg, stricture, achalasia. Inability to stand or sit upright for at least 30 mins.

However, your pharmacist may have suggested a different schedule that is more appropriate for you. Take it regularly and continuously to maintain its beneficial effects. Because it may cause esophageal irritation, this product must be swallowed with a large glass of water. Fosamax d 70 mg lying down for at least 30 minutes after taking it. It is not advisable to split, chew or crush this medication since it may irritate your mouth and gastrointestinal tract. Do not use more of this product, or more often, than prescribed.

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It helps your bones stay as strong as possible. This is where your bones get weaker and more likely to break. Osteoporosis can happen for many reasons, but you're more likely to fosamax d 70 mg it if you're a woman who has been through the menopause or if you take steroids, such as prednisolone, for a long time. Some types of cancer treatment can also increase your risk of getting osteoporosis. It comes as tablets, soluble tablets that dissolve in water to make a drink, or as a liquid that you drink.

Bisphosponates are prescribed to help your bones stay as strong as possible. Taking alendronic acid can help if you have, or are at risk of developing, osteoporosis. This is a condition that causes your bones to get weaker and be more likely to break. Osteoporosis can happen for many reasons, but you are more likely to get it if Talk to your doctor if you are worried about the health of your bones because of the medicines you take, or changes to your hormone levels because of the menopause.

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Alendronate is used to treat osteoporosis caused by menopause, steroid use, or gonadal failure. This medicine is for use when you have a high risk of bone fracture due to osteoporosis. You should not take alendronate if you are allergic to it, or if you have Do not take alendronate if you cannot sit upright or stand for at least 30 minutes. Alendronate can cause serious problems in the stomach or esophagus. You must stay upright for at least 30 minutes after taking this medicine.

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Sule, Efficacy of alendronate, a bisphosphonate, in the treatment of AVN of the hip. To study the efficacy of alendronate, in the treatment of avascular necrosis AVN of the hip. The most common cause of AVN was steroids. Parameters studied were walking time, standing time, pain and disability on a visual fosamax d 70 mg scale VAS, range of motion of the hip, X-ray and MRI of the hip. NSAIDs and analgesics were permitted as needed and were recorded. Six patients 10 hips required surgery and there were two three hips dropouts.

Alendronate sodium is a bisphosphonate that acts as a specific inhibitor of osteoclast -mediated bone resorption. Alendronate sodium is a white, crystalline, nonhygroscopic powder. Cholecalciferol vitamin D 3 is a fosamax d 70 mg that is the natural precursor of the calcium-regulating hormone calcitriol 1,25 dihydroxyvitamin D 3. Cholecalciferol is a white, crystalline, odorless powder. The optimal duration of use has not been determined.

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