Rosuvastatin calcium is a white amorphous powder that is sparingly soluble in water and methanol, and slightly soluble in ethanol. Lipid-altering agents should be used in addition to a diet restricted in saturated fat and cholesterol when response to diet and nonpharmacological interventions alone has been inadequate. The usual starting dose is 10 to 20 mg once daily. The usual starting dose in adult patients with homozygous familial hypercholesterolemia is 20 mg once daily. The tablet should be swallowed whole. After initiation or upon titration of CRESTOR, lipid levels should be analyzed within 2 to 4 weeks and the dosage adjusted accordingly.

After initiation or upon titration, analyze lipid levels within weeks and adjust dosage accordingly. Indicated as adjunctive therapy to diet to slow the progression of atherosclerosis in adult patients as part of a treatment strategy to lower total cholesterol and LDL cholesterol to target levels. Discontinue treatment if markedly elevated creatine kinase levels occur or myopathy is diagnosed or suspected; temporarily withhold in any patient with an acute, serious condition suggestive of myopathy or predisposing to the development of renal failure secondary to rhabdomyolysis eg, sepsis; hypotension; dehydration; major surgery; trauma; severe metabolic, endocrine, or electrolyte disorders; uncontrolled seizures. Limited data indicate that rosuvastatin is present in human milk; because statins have the potential for serious adverse reactions in nursing infants, women who require rosuvastatin treatment should not breastfeed their infants. SLCO1B1 polymorphism is thought to have a lesser effect on the more hydrophilic statins eg, rosuvastatin, fluvastatin compared with those that are more lipophilic eg, atorvastatin, pravastatin, simvastatin. Other genetic polymorphisms of elimination eg, CYP, P-glycoprotein for each individual drug must also be considered, to explain variability for statin clearance among patients that exhibit SCLO1B1 polymorphism. Your list will be saved and can be edited at any time.

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It belongs to a group of drugs known as statins. Lowering bad cholesterol and triglycerides and raising good cholesterol decreases the risk of heart disease and helps to prevent strokes and heart attacks. Talk with your doctor for more details. Indications: hypercholesterolemia, homozygous familial hypercholesterolemia, heterozygous familial hypercholesterolemia, hypertriglyceridemia, mixed hyperlipidemia, myocardial infarction prevention, primary dysbetalipoproteinemia, primary prevention of coronary heart disease, prevention of transient ischemic attack, prevention of cerebrovascular accident, atherosclerotic cardiovascular disease, hyperlipidemia. Many people using this medication do not have serious side effects. A very small number of people taking rosuvastatin may have mild memory problems or confusion. If these rare effects occur, talk to your doctor. Rarely, statins may cause or worsen diabetes. Talk to your doctor about the benefits and risks. Tell your doctor right away if this unlikely but serious side effect occurs: foamy urine.

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Ltd, Riyadh, Kingdom of Saudi Arabia; as. There is a wide inter-individual response to statin therapy including rosuvastatin calcium RC, and it has been hypothesized that genetic differences may contribute to these variations. The aim of this study is to demonstrate the interchangeability between two generic RC 20 mg film-coated tablets under fasting conditions among Mediterranean Arabs and to compare the pharmacokinetic results with Asian and Caucasian subjects from other studies. A single oral RC 20 mg dose, randomized, open-label, two-way crossover design study was conducted in 30 healthy Mediterranean Arab volunteers. Blood samples were collected prior to dosing and over a h period. Concentrations in plasma were quantified using a validated liquid chromatography tandem mass spectrometry method.

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Crestor is used in adults and children who are at least 8 years old to lower cholesterol and triglycerides in the blood. Crestor is used in adults to slow the progression of atherosclerosis a build-up of plaque in blood vessels that can block blood flow. Crestor is used to lower the risk of stroke, heart attack, and certain other heart complications in men 50 years and older and women 60 years and older who have coronary heart disease or other risk factors. For the heterozygous type, Crestor can be used in children who are at least 8 years old. For the homozygous type, this medicine can be used in children as young as 7 years old. Crestor can harm an unborn baby or cause birth defects.

Navigating middle school is tough: How parents can help. Preventable liver disease is rising: What you eat — and avoid — counts. When — and how — should you be screened for colon cancer? To fight back, the body sends white blood cells to trap the cholesterol, which then turn into foamy cells that ooze more fat and cause more inflammation. But the soft plaque beneath the purchase risperdal is dangerous.

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Crestor 20mg Tablet is a widely used medicine and is considered safe for long-term use. It may be taken with a meal or an empty stomach. You can take this medication at any time of the day so you can try to crestor rosuvastatin 20 mg tablet it at the same time every day. It is recommended that the cholesterol levels be checked regularly. This medicine is just one aspect of the recovery regimen and can also include proper diet, physical exercise, smoking reduction, alcohol consumption and weight loss.

Rosuvastatin is available as the brand-name drug Crestor. This purchase risperdal may be used as part of a combination therapy. This means you may need to take it with other medications. It also reduces your triglyceride level fats in your blood. These blockages can cause serious problems, including heart attack or stroke. A class of drugs is a group of medications that work in a similar way.

The clear evidence of the benefit of statin use coupled with very minimal side effects or long term effects has resulted in this class becoming one of the most widely prescribed medications in North America. Rosuvastatin and other drugs from the statin class of medications including atorvastatin, pravastatin, simvastatin, fluvastatin, and lovastatin are considered first-line options for the treatment of dyslipidemia. While all statin medications are considered equally effective from a clinical standpoint, rosuvastatin is considered the most potent; doses of 10 to 40mg rosuvastatin per day were found in clinical studies to result in a A governmentally-recognized ID which uniquely identifies the product within its regulatory market. It is also indicated for the prevention of major cardiovascular events including risk of myocardial infarction, nonfatal stroke, and coronary artery revascularization in adult patients without documented history of cardiovascular or cerebrovascular events, but with at least two conventional risk factors for cardiovascular disease.

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