This randomized controlled study was conducted between November and May One hundred and twenty patients were randomly allocated to 3 groups. Forty patients were in the paracetamol 1 gram group, 40 in the ibuprofen mg group and 40 in the diclofenac potassium 50 mg group. Evaluation of the post extraction and deep cavity preparations pain was made by patients immediately postoperatively, 2, 4 and 6 hours postoperatively on standard mm visual analogue scales VAS. Furthermore, each patient was observed preoperatively and immediately postoperatively for signs of distress by using a 5 point face scale. Changes in distress scores from the preoperative score to the postoperative score were made using the paired sample t-test. Diclofenac potassium was more effective than paracetamol or ibuprofen for reducing postoperative pain associated with tooth extraction and deep cavity preparation.

Undesirable effects may be minimised by using the lowest effective dose for the shortest duration necessary to control symptoms see section 4. In particular it is recommended that the lowest effective dosage be used in frail elderly patients or those with a low body weight see also precautions and the patient should be monitored for GI bleeding during NSAID therapy. Patients with congestive heart failure NYHA-I or significant risk factors for cardiovascular disease should be treated with diclofenac only after careful consideration. Since cardiovascular risks with diclofenac may increase with dose and duration of exposure, the lowest effective daily dose should be used and for the shortest duration possible see section 4. Renal impairment: Diclofenac is contraindicated in patients with renal failure see section 4. No specific studies have been carried out in patients with renal impairment, therefore, no specific dose adjustment recommendations can be made.

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GI disturbances; headache, dizziness, rash; GI bleeding, peptic ulceration; abnormalities of kidney function. Potentially Fatal: Stevens-Johnson syndrome, exfoliative dermatitis, toxic epidermal necrolysis. Renal function may be worsened when used with ciclosporin or triamterene. Altered absorption when given with sucralfate, colestyramine or colestipol. Ophthalmic application of diclofenac may reduce the efficacy of ophthalmic acetylcholine and carbachol. Increased risk of GI ulceration and bleeding when used with corticosteroids, aspirin or anticoagulants. Potentially Fatal: Increases blood levels of digoxin, lithium and methotrexate. Potentiate potassium-sparing diuretics. Treatment of perioperative pain in CABG surgery. Diclofenac has potent anti-inflammatory, analgesic and antipyretic actions.

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Novartis, in, has made an online launch of Voltaflam TH, as part of its life cycle management strategy. The discontinuation of Volflam 50 mg could be decided after this matter gets decided by the Court, said the Authority in a recent meeting. This demand was challenged by the company before the Delhi High Court. In the opinion of the company, Voveran 50 GE tablet is not covered under the category of essential medicines under the National List of Essential Medicines and, hence, is a non-scheduled drug under DPCO, As part of its life-cycle management strategy, the company during the fiscal year launched Voltaflam TH, a new product in the combination market for treatment of pain due to muscle spasm, online. The success of this initiative will pave the way for more such ventures in the future, it said.

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Common side effects include abdominal pain, gastrointestinal bleeding, nausea, dizziness, headache, and swelling. Diclofenac was patented in by Ciba-Geigy ; it came into medical use in the United States in Diclofenac is used to treat pain, inflammatory disorders, and dysmenorrhea. An additional indication is the treatment of acute migraines. It may also help with actinic keratosis, and acute pain caused by minor strains, sprains, and contusions bruises.

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However, these are only indicative and not all patients will experience them. Do not use Voveran 50mg GE Tablet if you are allergic to - Diclofenac If you have heart disease, liver or kidney disease, drug or alcohol addiction, consult your doctor before using Voveran 50mg GE Tablet. If you are allergic to any medicine or food, consult your doctor before using this medicine. Use this medicine under the supervision of your doctor. The dosage of Voveran 50mg GE Tablet depends on many factors such as the patient age, health, medical condition or history of the patient and many other conditions.

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