Objective: To evaluate the cost-effectiveness of tamsulosin, doxazosin, or terazosin as initial treatments for moderate benign prostatic hyperplasia BPH over a 3-year time horizon from a health-system-payer perspective. The ranges of values for treatment failure rates and clinical event cost parameters used in the decision model are derived from the literature. Effectiveness is measured as successful medical treatment without surgery over 3 years. The model estimates a medical treatment success rate no TURP at 3 years of The incremental cost for tamsulosin versus terazosin is dollars over 3 years, which yields an incremental cost-effectiveness ratio of 14, dollars per success.

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