FOSAMAX alendronate sodium is a bisphosphonate that acts as a specific inhibitor of osteoclastmediated bone resorption. FOSAMAX is indicated for the treatment of glucocorticoid -induced osteoporosis in men and women receiving glucocorticoids in a daily dosage equivalent to 7. Patients at low-risk for fracture should be considered for drug discontinuation after 3 to 5 years of use. Patients with gastrointestinal malabsorption syndromes may require higher doses of vitamin D supplementation and measurement of 25hydroxyvitamin D should be considered. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice. The safety of FOSAMAX in the treatment of postmenopausal osteoporosis was assessed in four clinical trials that enrolled women aged years.

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Couldn't load pickup availability Refresh. Active ingredient Alendronate sodium hydrate. Effects of this medicine This medicine suppresses bone resorption by acting upon cells osteoclasts which destroy bone tissue, thereby increasing bone mass and making bones resistant to fractures. It is usually used to treat osteoporosis. Avoid chewing or sucking this medicine. Do not take this medicine before going to bed or while lying in bed. If you have taken some foods or beverages, skip the missed dose for the day and take a dose at the time of awaking the next day. Thereafter, return to your designated dosing date and schedule. You should never take two doses at one time. Some medicines may interact to enhance or diminish medicinal effects.

In, the FDA approved alendronate Fosamax for the fosamax 35 mg tablet of postmenopausal osteoporosis, a bone-weakening condition that affects more than eight million women and causes 1. Fractures are an important cause of disability and death in postmenopausal women. Hip fractures lead to hospitalization and, usually, surgery — and they often result in nursing home care. Vertebral fractures can cause debilitating back pain, and they, too, increase the risk of premature death. We know, for example, that it improves bone density for at least 10 years.

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Conclusions: Treating older osteoporotic women with alendronate was more cost effective than treating younger women with osteoporosis, and treating osteoporotic women with prior spine fracture was more cost. The bioequivalence and pharmacokinetics of alendronate sodium tablets were examined by determining the plasma concentration of alendronate. Two groups, consisting of 24 healthy volunteers. The rare domain name InnovivePharma. Canada Number Analyzed 70 participants 70 participants participants.

This drug has been used for treatment of osteoporosis associated with Crohn's disease and for hypercalcemia. Generic Name: Alendronate no generic available, U. Popularity: 29th most commonly prescribed drug between U. Class: Calcium regulator bisphosphonate. Treatment Uses For prevention and treatment of postmenopausal osteoporosis women, treatment of osteoporosis in men, and treatment of steroid induced osteoporosis in men and women.

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Learn about the medical, dental, pharmacy, behavioral, and voluntary benefits your employer may offer. Do not take alendronate if you cannot sit upright or stand for at least 30 minutes after taking the medicine. Alendronate can cause serious problems in the stomach or esophagus. This medicine is for use when you have a high risk of bone fracture due to osteoporosis. Do not take alendronate if you cannot sit upright or stand for at least 30 minutes.

It is used to treat and prevent osteoporosis weak or brittle bones in Postmenopausal Women. It helps to improve bone mass density in patients with weak bones and can also be used to treat osteoporosis caused due to excessive use of corticosteroids such as prednisone. Alendronic acid prevents bone loss and helps in building bone mass and density. It works by attaching itself to the bone surface and then stops the action of certain bone cells that destroys the bone mass. It also stabilizes the replacement of new bone tissue growth and prevents abnormal bone growth.

Fosamax contains the active drug alendronate. A class of medications is a group of drugs that work in a similar way. Fosamax works to decrease bone breakdown in your body and make your bones stronger. In clinical trials, the drug was only studied in people for up to 4 years. Your doctor may have you stop taking Fosamax after 3 to 5 years.

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