Z, age 27, seeks treatment for substance abuse at a mental health clinic. He has a 7-year substance use history and his last urine drug screen 1 month ago was positive for marijuana, opiates, and benzodiazepines. Z often takes quetiapine while smoking marijuana. He sleeps well with this and does not experience a hangover effect. Methods of quetiapine misuse include ingesting pills, inhaling crushed tablets, and injecting a solution of dissolved tablets. Efforts to treat inmates for substance use disorders may be thwarted by the easy availability of drugs in correctional settings.

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