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What is modafinil, and how does it work mechanism of action? Modafinil is an oral drug that is used for improving wakefulness in patients with excessive sleepiness. It is similar to armodafinil Nuvigil. Like amphetamines, modafinil promotes wakefulness by stimulatIng the brain.

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Provigil may be used alone or with other medications. Consideration should be given to the use of lower doses and close monitoring in geriatric patients see Use in Specific Populations. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. The adverse reaction profile was similar across these studies.

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