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This Application claims benefit of U. Provisional Application Ser. The present invention relates to compositions that include modafinil and one or more diluents, disintegrants, binders and lubricants. Modafinil, C 15 H 15 NO 2 S, also known as 2- benzhydrylsulfinyl acetamide, or 2- diphenylmethyl sulfinyl acetamide, is a synthetic acetamide derivative with wake-promoting activity, the structure of which has been described in French Patent No. Modafinil has been tested for treatment of several behavioral conditions in combination with various agents including apomorphine, amphetamine, reserpine, oxotremorine, hypnotics, yohimbine, 5-hydroxytryptophan, and monoamine oxidase inhibitors, as described in the cited patents. A method of preparation of a racemic mixture is described in the ' patent and a method of preparation of a levorotatory isomer is described in U. The primary pharmacological activity of modafinil is to promote wakefulness. Modafinil promotes wakefulness in rats Touret et al. Modafinil has also been described as an agent with activity in the central nervous system, and as a useful agent in the treatment of Parkinson's disease U.

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