We describe the outcomes of 16 cases of imported loiasis in Italy. This combination might be an effective treatment option in nonendemic areas, when diethylcarbamazine, the drug of choice, is not available. Loa loa is a filarial nematode transmitted by tabanid flies of the genus Chrysops, which inhabits forested areas of West and Central Africa 1. Adult worms move under the skin or in the intermuscular fascia and can produce microfilariae. Loiasis can cause a wide range of symptoms, most frequently migrant edemas Calabar swellings. Three drugs are currently used to treat loiasis: diethylcarbamazine, ivermectin, and albendazole 4.

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