Tramadol HCL is an opioid drug prescribed to treat moderate to severe pain, sometimes including chronic pain. Despite being a lower-potency opioid when compared with other common pain medications, tramadol can still be addictive if abused. Prolonged tramadol abuse can lead to worsened side effects, physical dependence, cravings, and long-lasting withdrawal symptoms. Because of this, healthcare professionals may recommend opioid addiction treatment. Professional substance use disorder treatment includes medical detoxification, behavioral therapy, medication-assisted treatment, and other evidence-based treatment options.

Tramadol Stada: Oral drops: 1 ml solution equivalent to 40 drops contains: Tramadol hydrochloride mg, Potassium sorbate 1. Injection: 1 ampoule of 2 ml injectable solution contains: Tramadol hydrochloride mg, Sodium acetate, Water for injection. Tramadol Stada 1 capsule contains: Tramadol hydrochloride 50 mg, calcium hydrogen phosphate 2H 2 O, gelatins, magnesium stearate, colloidal anhydrous silica, coloring agent E Pharmacology: Tramadol hydrochloride is a cyclohexanol derivative with central analgesic and antitussive activities. In addition to opiate agonist activity, Tramadol inhibits re-uptake of certain monoamine norepinephrine, serotonin which appears to contribute to the drug's analgesic effect. Unlike morphine, Tramadol has no respiratory depressant effect over a wide range of analgesic doses. It also does not affect gastrointestinal motility.

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The misuse of tramadol has become a major aspect of the wider substance use challenge in recent years and is evolving into a health crisis at an alarming rate. However, literature on motivations for non-medical purpose tramadol use among commercial vehicle operators remains inadequate. The aim of this study was to document the motivations for non-medical purposes tramadol use in Kumasi. We conducted this exploratory qualitative study with 23 purposively selected commercial vehicle drivers 15 and assistants 8 in Kumasi, Ghana. Based on the findings of the study and the dependence and addictive potentials of tramadol, there is the need for psychoeducational programmes for persons who misuse tramadol and enhancement of operational capacities of regulatory agencies. However, misuse and dependence of tramadol, especially among the youth, manual workers, market women, commercial vehicle driversand students 4 in recent times has become a serious global issue in many countries, especially in Africa, Asia and Middle East 5, 6, 7, 8. In the US, statistics indicate that 3. In Africa, accurate statistics of the level of tramadol misuse are largely unknown as a result of limited epidemiological research on the drug. For instance, in Nigeria, tramadol misuse has a prevalence of approximately The Ghana Health Service has declared the issue as a national concern and putting in place measures such as seizures to control it.

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