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Tramadol is a pain medicine similar to an opioid and is classified as a synthetic opioid. It acts in the central nervous system CNS to relieve pain. Tramadol is an FDA-approved medication for pain relief. It has specific indications for moderate to severe pain. Due to possible misuse disorder potential, limitations to its use should be for pain that is refractory to other pain medication, such as non-opioid pain medication. This activity outlines the indications, mechanism of action, methods of administration, important adverse effects, contraindications, toxicity, and monitoring, of tramadol so providers can direct patient therapy where it is indicated as part of the interprofessional team. Dosage should be individualized based on pain severity, therapy response, prior treatment experience and risk factors of addiction, abuse and misuse. Adults 17 years or older: 50 to mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: mg per day. Take tramadol exactly as prescribed by your doctor. Never use tramadol in larger amounts, or for longer than prescribed.

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Tramadol has been discontinued and replaced by Tapentadol Generic Nucynta. Both medications are considered opioid agonists, but Tramadol is significantly weaker than Tapentadol. Tramadol and tapentadol both inhibit the reuptake of norepinephrine to roughly the same degree, but tramadol inhibits serotonin reuptake 3 times more than tapentadol. Please use Mastercard, Amex or Bitcoin. We have a huge backlog of orders but all orders will be shipped out ASAP with the fastest shipping method available - Express Mail and Couriers. Why is Tramadol medication prescribed?

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