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Egyptian President Abdel Fattah al-Sisi announced Monday his candidacy for a third term in office, ahead of December elections he is widely expected to win. A year after deposing Islamist president Mohamed Morsi, Sisi won 96 percent of the vote in This time, as Egyptians grow increasingly frustrated with an unrelenting economic crisis, presidential hopefuls have emerged from the woodwork of an opposition decimated by Sisi's decade-long crackdown on dissent. Without parliamentary backing, the year-old will need to collect 25, nominations from Egyptians across at least 15 governorates by October 14 to be eligible. If elected, Sisi's third term would be his last, according to a constitutional amendment he pushed through in

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These are the International Classification of Diseases (ICD- Revised. With these systems, a diagnosis of mental disorders is made from the presence of specific symptoms or a syndrome for a minimum of two weeks. This relies on the skills of recognizing patterns of symptoms. It is not based on pathology, diagnostic tests or the presence or absence of an immediate cause.

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Psychiatric disorders include types of depression, psychosis and anxiety. Neurological disorders include Parkinsons disease, epilepsy and Alzheimers disease. There are many neurotransmitters that carry information from neurone to neurone in the nervous system.

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Neurotransmitters in the RAS are serotonin and GABA. It is thought that GABA normally moderates the activity of serotonin-containing neurons and that in anxiety syndromes some of this moderation is lost due to changes in receptor sensitivity, or due to overactivity of a natural inhibitor of GABA. An inhibitor of GABA has not been identified, but it has been tentatively called GABA modulin. It is possible that the RAS can be activated through pathways from the cerebral cortex if a situation is perceived as being threatening. Sleep is complicated and involves the brain stem RAS.

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