Indication Rectal administration of diazepam DZP for the treatment of seizure emergencies is safe and effective, reduces medical costs, and improves quality of life, but many patients and their caretakers are reluctant to consider this mode of therapy especially when the patient is in a location which is socially embarrassing 7 - Factors that may affect the price you'll pay include your treatment plan, your insurance coverage, and the pharmacy you use. Instead of Medicare, Use a Coupon. No Image ; Valeant Pharmaceuticals ; Diazepam 2.

The drugs in this group have a calming effect, relieve tension and relax the muscles. In these cases, there are high levels of carbon dioxide in the blood, which is mostly due to poor pulmonary ventilation; in preterm newborn diazepam 10mg rectal gels during the first 30 days of life or in children under the age of one year. Unusual paradoxical reactions Sometimes it is possible occurrence of such effects, especially in elderly or frail, and in children. Instead the occurrence of fatigue and relief stimulate adverse effects such as restlessness, agitation, irritability, aggression, delusions, intense anger, nightmares, hallucinations, psychoses, inappropriate behavior or other behavioral problems. At constant or regular use for a long time Possible development of tolerance and dependence on diazepam.

People who experience seizure activity epilepsy often take anti-seizure medicine to control the condition. However, sometimes additional medicine may be needed to control bouts of increased seizure activity cluster seizures or breakthrough seizures. The Diastat AcuDial rectal administration system contains the medicine diazepam, rectal gel, to manage these breakthrough seizures.

Diazepam Rectal Gel rectal delivery system is a non-sterile diazepam gel provided in a prefilled, unit-dose, rectal delivery system. Diazepam Rectal Gel is clear to slightly yellow and has a pH between 6. Pediatrics: No pharmacokinetic studies were conducted with Diazepam Rectal Gel in the pediatric population. A randomized, double-blind study compared sequential doses of Diazepam Rectal Gel and placebo in 91 patients 47 children, 44 adults exhibiting the appropriate seizure profile.

WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. Diazepam rectal is an general anesthetic that is FDA approved for the treatment of refractory, patients with epilepsy, on stable regimens of AEDs. Common adverse reactions include hypotension, rash, diarrhea, muscle weakness, ataxia, incoordination, somnolence, euphoria, respiratory depression, and fatigue.

Apply this medicine only as directed by your doctor. does not endorse companies or products. Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine. Alumni Association. International Business Collaborations.

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At the point of sale, have the patient or caregiver check each syringe to ensure that the correct dose has been locked. Challenges Pertaining to Elderly Patients. The Diastat AcuDial delivery system is available as a mg or mg rectal syringe designed to deliver minimum dosages of 5 mg or Before the product is dispensed, both diazepam 10mg rectal gels must be dialed, set, and locked to the prescribed dose by the pharmacist, even when the maximum dose is prescribed.

Alzheimer's Disease: Empowering Patients and Caregivers. In one case, a 4-year-old girl with complex seizure disorder was prescribed Diastat AcuDial 5 mg. Pharmacists Pet Peeves: September Interactive Case Studies: September Conferences Conference Coverage. Living with Osteoarthritis. The pharmacy, however, dispensed an unlocked mg Diastat AcuDial rectal syringe. Ensure that each pharmacist is taught how to dial, set, and lock the dose for the Diastat AcuDial rectal syringe.

Consider building an alert into the pharmacy computer system to notify the pharmacist that the dose must be dialed and locked. A second case involved a young boy weighing 8 kg who had complex partial seizure disorder. To check that the correct dose has been selected, incorporate an independent double check with a second pharmacist or pharmacy technician before the dose is locked. Pharmacists Pet Peeves: September September 21st Interactive Case Studies: September September 20th Chronic Lymphocytic Leukemia.

Unfortunately, unlike the case above, the parents were not educated on what to check for when using Diastat AcuDial. It is important to check that the dose has been dialed correctly and locked for both syringes. Publications All Publications. Some of these errors have led to respiratory depression and required emergent intervention. Respiratory Syncytial Virus. The child developed respiratory depression, was transported to the emergency department, and thankfully recovered.

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It is used for the intermittent treatment of severe seizures also known as recurrent, serial, cluster, or crescendo seizures that occur for certain people even though they take regular doses of medications to treat epilepsy. Diazepam rectal gel usually starts controlling seizures 5 to 15 minutes after it is used. It works by slowing down the nerves in the brain i.

Your medication may look different. If you have questions, ask your pharmacist. Generic name: Diazepam - rectal.

Calculate dose based on body weight in kg and round up to next available dosage strength. Treat no more than 1 episode every 5 days and no more than 5 episodes per month. See full labeling for dosing chart. Elderly or debilitated: reduce dose.

Some of these errors have led to respiratory depression and required emergent intervention. In one diazepam 10mg rectal gel, a 4-year-old girl with complex seizure disorder was prescribed Diastat AcuDial 5 mg. The pharmacy, however, dispensed an unlocked mg Diastat AcuDial rectal syringe. A second case involved a young boy weighing 8 kg who had complex partial seizure disorder.

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