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Medindia» Drugs» Drug Price» Diazepam. Diazepam Valium generic is a benzodiazepine, prescribed for anxiety. It is also diazepam to buy online for muscle spasms and seizures. Drug Name: Diazepam Diazepam Valium generic is a benzodiazepine, prescribed for anxiety. Online hearing tests enable you to test your hearing to check slow or sudden hearing loss right at your home.

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After absorption, diazepam is redistributed into muscle and adipose tissue. Absorption appears to depend on several factors, such as temperature, concentration, flow rates, and tube length. Use of diazepam should be avoided, when possible, in individuals with: Benzodiazepines such as diazepam can cause anterograde amnesia, confusion, and sedation. These interactions would be expected to be most significant with long-term diazepam therapy, and their clinical significance is variable.

It easily crosses both the blood—brain barrier and the placenta, and is excreted into breast milk. Diazepam is sometimes used intermittently for the prevention of febrile seizures that may occur in children under five years of age. At a particularly high risk for diazepam misuse, substance use disorder or dependence are Patients from the diazepam cheap groups should be monitored very closely during therapy for signs of abuse and development of dependence.

Withdrawal symptoms can sometimes resemble pre-existing conditions and be misdiagnosed. Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that acts as an anxiolytic. Because flumazenil is a short-acting drug, and the effects of diazepam can last for days, several doses of flumazenil may be necessary. Benzodiazepines have a relatively low toxicity in overdose. Intravenous diazepam or lorazepam are first-line treatments for status epilepticus.

Diazepam is a good choice for tapering for those using high doses of other benzodiazepines since it has a long half-life thus withdrawal symptoms are tolerable. Because of its relatively long duration of action, and evidence of safety and efficacy, diazepam is preferred over other benzodiazepines for treatment of persons experiencing moderate to severe alcohol withdrawal. Improper or excessive use of diazepam can lead to dependence. The muscle relaxant properties of diazepam are produced via inhibition of polysynaptic pathways in the spinal cord.

These metabolites are conjugated with glucuronide, and are excreted primarily in the urine. Its other active metabolites include the minor active metabolites temazepam and oxazepam. Long-term use of benzodiazepines such as diazepam induces tolerance, dependency, and withdrawal syndrome. Diazepam was patented in by Hoffmann-La Roche.

Diazepam may impair the ability to drive vehicles or operate machinery. As a result, the arousal of the cortical and limbic systems in the central nervous system is reduced. Diazepam can be synthesized from nordazepam by methylating the R1 position using dimethyl sulfate. Diazepam is highly lipid-soluble, and is widely distributed throughout the body after administration. Hypotension may be treated with levarterenol or metaraminol.

Drug tolerance may also develop to infusions of diazepam if it is given for longer than 24 hours. Rebound anxiety, more severe than baseline anxiety, is also a common withdrawal symptom when discontinuing diazepam or other benzodiazepines. The main active metabolite of diazepam is desmethyldiazepam also known as nordazepam or nordiazepam. Diazepam is mainly used to treat anxiety, insomnia, panic attacks and symptoms of acute alcohol withdrawal.

Binding of benzodiazepines to this receptor complex promotes the binding of GABA, which in turn increases the total conduction of chloride ions across the neuronal cell membrane.

Indications for use of Valium include a short-term treatment of neurotic and neurosis-like disorders with the manifestation of anxiety, which may also be associated with insomnia. Relief of psychomotor agitation associated with anxiety. Relief of epileptic seizures and convulsive states of various etiologies in combination with other anticonvulsant drugs.

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