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Sildenafil, sold under the brand name Viagra, among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. Common side effects include headaches, heartburn, and flushed skin. Sildenafil acts by blocking phosphodiesterase 5 PDE 5, an enzyme that promotes breakdown of cGMP, which regulates blood flow in the penis. Pfizer originally discovered the medication in while looking for a treatment for angina.

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Elizabeth Nichols is an orthopaedic and flexible author with unipolar experience in both popular media and bacterial publishing. She specializes in osteoporosis, medical and travel writing. Ultimate Facts About Viagra First put on the formation in by Pfizer, Viagra works by attaching the enzyme phosphodiesterase 5 PDE5, which in release relaxes the blood vessels in the body.

Pesky Enzyme Sidelined In men with vascular problems. The urethra carries urine from the bladder and semen from the body. What many people forget is that old age will come and things might not be the right choice for every man, but in general, the medication is very successful at treating erectile dysfunction.

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This class of medications work by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Importantly, Sildenafil does not increase sexual desire or cure erectile dysfunction. Revatio was approved for management of pulmonary hypertension.

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