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Air embolism is a rare but life-threatening complication. Techniques that puncture the skin can introduce infection through poor aseptic technique or contaminated equipment. Antihistamines and corticosteroids, if needed for adverse reactions, should never be mixed in the same syringe because precipitation would occur. Contrast agents are among the safest medicinal products in use. They are not intended to have pharmacological activity; nevertheless adverse reactions are possible.

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Radiographers, and other staff, should be adequately trained and educated in support of reducing risk to patients and also improving care and management (Society and College of Radiographers, to offer in-house training for those who wish to use PGDs and such courses are likely to include: stated outcomes; assessment that verifies the outcomes have been attained; remedial procedures for those who do not pass. The stated outcomes of PGDs are: Understand the concept of patient group directions Understand the historical and legal background to patient group directions Understand the meanings of pharmacodynamics and pharmacokinetics in relation to the drugs that the radiographer is able to supply and administer Understand the pathophysiological processes in the conditions under which the patient group directions can be used Understand the protocols and guidelines that exist to support the use of patient group directions. Supplementary prescribing courses are offered by universities and these are open to all professions that are legally permitted to hold these responsibilities. Presently, ring-fenced monies from the Department of Health are managed by Strategic Health Authorities to fund these courses in an attempt to promote non-medical prescribing.

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